necrolysis /ne·crol·y·sis/ (nĕ-krol´ĭ-sis) separation or exfoliation of necrotic tissue.
necrolysis
toxic epidermal necrolysis a severe cutaneous reaction, primarily to drugs, but also due to other causes such as infections or neoplastic disease, characterized by bulla formation, subepidermal separation, and widespread loss of skin, leaving raw denuded areas.
ne·crol·y·sis (n -kr l  -ss)n. Necrosis and loosening of tissue. |
necrolysis
[nekrol′isis]
Etymology: Gk, nekros + lysis, loosening
disintegration or exfoliation of dead tissue. Compare necrosis. necrolytic, adj.
necrolysis
separation or exfoliation of necrotic tissue.
toxic epidermal necrolysis
an acute exfoliative disease of skin and mucous membranes in dogs, cats and monkeys. Characterized by full thickness epidermal necrosis and accompanied by erythema, vesicles, bullae and ulcers, and systemic signs of fever, anorexia and lethargy. It is associated with concurrent infections or neoplasia, and drug reactions.
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