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necrolysis |
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necrolysis /ne·crol·y·sis/ (nĕ-krol´ĭ-sis) separation or exfoliation of necrotic tissue.
toxic epidermal necrolysis a severe cutaneous reaction, primarily to drugs, but also due to other causes such as infections or neoplastic disease, characterized by bulla formation, subepidermal separation, and widespread loss of skin, leaving raw denuded areas.
necrolysis [nekrol′isis] Etymology: Gk, nekros + lysis, loosening disintegration or exfoliation of dead tissue. Compare necrosis. necrolytic, adj. necrolysis [nĕ-krol´ĭ-sis] separation or exfoliation of necrotic tissue. toxic epidermal necrolysis an exfoliative skin disease in which erythema spreads rapidly over the body, followed by blisters much like those seen in a second degree burn. It may be caused by drug reactions, infections (viral, bacterial, or fungal), neoplastic disease, graft-versus-host reaction, and chemical exposure.
necrolysis separation or exfoliation of necrotic tissue. toxic epidermal necrolysis an acute exfoliative disease of skin and mucous membranes in dogs, cats and monkeys. Characterized by full thickness epidermal necrosis and accompanied by erythema, vesicles, bullae and ulcers, and systemic signs of fever, anorexia and lethargy. It is associated with concurrent infections or neoplasia, and drug reactions. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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