necrobiotic granulomas

necrobiotic granulomas

granulomas that share some of the characteristics of both immunological and nonimmunological collections of mononuclear phagocytes. Relatively acellular areas of the skin become necrobiotic, and the collagen assumes a homogenous, amorphous appearance. See also granuloma annulare, necrobiosis lipoidica.
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These are Tuberculous granulomas, Lepromatous granulomas, Foreign Body granulomas, Necrobiotic granulomas, Suppurative granulomas, Sarcoidal granulomas and Xanthgranulomas/ malakoplakia.
Research variables were; types of cutaneous granuloma with attributes of tuberculous granuloma, cutaneous leishmaniasis, fungal granuloma, foreign body granuloma, leprosy, sarcoid granuloma, malakoplakia and necrobiotic granuloma.
In particular, isolated rheumatoid nodules or necrobiotic granulomas (deep granuloma annulare) have a decided potential for this mimicry, vis-a-vis the alternative diagnosis of epithelioid sarcoma.
Histologically, epithelioid sarcoma and isolated necrobiotic granulomas may also be similar.