necrobiotic granulomas

necrobiotic granulomas

granulomas that share some of the characteristics of both immunological and nonimmunological collections of mononuclear phagocytes. Relatively acellular areas of the skin become necrobiotic, and the collagen assumes a homogenous, amorphous appearance. See also granuloma annulare, necrobiosis lipoidica.
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In particular, isolated rheumatoid nodules or necrobiotic granulomas (deep granuloma annulare) have a decided potential for this mimicry, vis-a-vis the alternative diagnosis of epithelioid sarcoma.
Histologically, epithelioid sarcoma and isolated necrobiotic granulomas may also be similar.
Evans CS, Goldman RL, Klein HZ, et al: Necrobiotic granulomas of the uterine cervix.