After a chapter on the structure and function of skin, volume one covers disorders of keratinization; inherited and autoimmune subepidermal blistering diseases; acantholytic disorders; spongiotic, psoriasiform, and pustular dermatoses; superficial and deep perivascular inflammatory dermatoses; granulomatous, necrobiotic
, and perforating dermatoses; inflammatory diseases of the subcutaneous fat; diseases of the oral mucosa; diseases of the genital skin; degenerative and metabolic diseases; cutaneous adverse reactions to drugs; neutrophilic and eosinophilic dermatoses; vascular diseases; idiopathic connective tissue disorders; and infectious diseases of the skin.
The exact relation between granuloma annulare and diabetes, necrobiotic
granuloma, and rheumatoid nodules has been debated (24, 25).
Evans CS, Goldman RL, Klein HZ, et al: Necrobiotic
granulomas of the uterine cervix.
Microscopy findings included signs of focal encephalitis and vasculitis, lymphocytic perivascular inflammatory infiltration, profound degenerative and necrobiotic
changes of ganglion cells in the cerebral cortex, and signs of brain edema, as well as parenchymal myocarditis (stromal edema, degeneration of myocytes, foci of myolysis, and fragmentation of myofibrils).
It consists of seventeen Arabic star names expanded like acronyms into short, acrostic aphorisms (for example, Gienah becomes "Gide, in extremis, necrobiotic
, Almost hegelian").
nodules are often located subpleurally and surrounded by palisading histiocytes and giant cells.