necrobiosis li·poi·di·ca (l -poi d-k )n. A condition, occasionally associated with diabetes, in which shiny atrophic lesions develop on the legs. Also called necrobiosis lipoidica diabeticorum. |
necrobiosis lipoidica
[lipoi′dikə]
Etymology: Gk, nekros, dead, bios, life, lipos, fat, eidos, form
a skin disease characterized by thin, shiny, yellow-to-red plaques on the shins or forearms. Telangiectases and crusting and ulceration of these plaques may occur. Necrobiosis lipoidica is usually associated with diabetes mellitus and occurs most often in women. Treatment includes precise control of the diabetes and, possibly, intralesional application of corticosteroids.
necrobiosis [nek″ro-bi-o´sis]
the physiologic death of cells; a normal mechanism in the constant turnover of many cell populations. Called also bionecrosis. adj., adj necrobiot´ic.
necrobiosis lipoi´dica a dermatosis characterized by patchy degeneration of the elastic and connective tissue of the skin with degenerated collagen occurring in irregular patches, especially in the dermis, most often on the mid or lower shins; usually associated with diabetes.
necrobiosis lipoidica
Dermatology An inflammatory condition seen in 50-80% of DM, most often on the legs; in 10%, NL precedes onset of DM. See Non-insulin-dependent diabetes mellitus.
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