nebulin


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neb·ul·in

(neb'yū-lin), [MIM*161650]
A large protein, constituting about 3% of skeletal muscle protein; may aid in the organization of actin filaments as well as in actin polymerization.
[L. nebula, mist, fog, fr. G. nephelē, + -in]

nebulin

(neb′yŭ-lin)
A large protein (600 to 800 kD in mass) found in the thin filaments of contractile muscles, where it binds to actin.
References in periodicals archive ?
Detection of giant myofibrillar proteins connectin and nebulin in fish meat by electrophoresis in 3-5 gradient sodium dodecyl sulfate polyacrylamide slab gels.
Architecture of the sarcomere matrix of skeletal muscle: immunoelectron microscopic evidence that suggests a set of parallel inextensible nebulin filaments anchored at the Z line.
Recent studies have indicated that CAPN3 could cleave titin (related to the remodeling of sarcomere), filamin C (the Z-disc of the myofibrillar apparatus by binding directly to the Z-disc proteins FATZ (a filamin-, actinin-, and telethonin-binding protein of the Z-disc of skeletal muscle) and myotilin) and nebulin (the autolysis of myofibrillar CAPN3 and CAPN1), respectively (Faulkner et al.