Imago BioSciences translates unique insights into high impact transformative therapies that alter the natural history of disease
allowing patients to live longer, disease-free lives.
Funded activities will provide a principal US pediatric vaccine-preventable (and potentially vaccine preventable) disease surveillance system, to include actively assessing a wide spectrum of AGE, ARI and influenza pathogens, evaluations of vaccine effectiveness for licensed vaccines, burden and natural history of disease
for pathogens having upcoming and/or new vaccines, pediatric infectious disease transmission dynamics, vaccination/therapeutic policy and development, vaccine impacts for targeted and vulnerable populations, and socioeconomic and microbiological environments potentially relevant to these public health interventions.
We propose that routine or targeted screening with chest CT at the time of aortic aneurysm diagnosis may be indicated, not only to really define the natural history of disease
, but more importantly to try to prevent late aortic events," Dr.
New and updated information includes new disease outbreaks, the history of epidemiology and the natural history of disease
, morbidity and mortality data, health disparities, data sources, and professional issues in epidemiology.
The ideal marker test would be able to accurately stage disease and also be sensitive to changes in fibrosis induced by therapy or the natural history of disease
The natural history of disease
is largely unpredictable in a given patient.
For example, community health nursing teaches the concepts of natural history of disease
, which include health promotion and prevention, early diagnosis and treatment, and rehabilitation.
Multi-Year Collaboration to Use Clinically Relevant Biomarkers in Natural History of Disease
Study to Improve Quality of Translational Alzheimer's Drug Development
We expect that the results from this first-in-human clinical study of RG-012, combined with our learnings from our natural history of disease
study called ATHENA, will provide the clinical basis for the design of a proof-of-concept study to monitor the therapeutic effect of RG-012 in Alport syndrome patients.
COPAXONE([R]) Treatment Favorably Effected Natural History of Disease
Currently, we are enrolling Alport syndrome patients in ATHENA, our global natural history of disease
study, and expect to initiate a Phase I study in healthy volunteers in the first half of 2015 and a Phase II proof-of-concept study thereafter.
In the near term, Regulus expects to initiate a natural history of disease
study to gather further information about the progression of Alport syndrome and to inform future clinical development plans of RG-012, a key program under Regulus' 'Clinical Map Initiative'.