natural antibody


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nor·mal an·ti·bod·y

antibodies occurring as a result of immunoglobulin DNA rearrangement and somatic hypermutation rather than in response to stimulation with a specific antigen.
Synonym(s): natural antibody

natural antibody

[nach′(ə)rəl]
Etymology: L, natura, nature; Gk, anti + AS, bodig, body
an antibody that is present in serum in the absence of an apparent specific antigen contact.

natural antibody

An antibody (e.g., anti-A, anti-B blood group antibodies) that is present in the circulation without prior exposure to the cognate antigen.

natural antibody

Normal antibody An antibody present in the circulation, without prior exposure to its cognate antigen

nor·mal an·ti·body

(nōr'măl an'ti-bod-ē)
Antibody demonstrable in the serum or plasma of various people or animals not known to have been stimulated by specific antigen, either artificially or as the result of naturally occurring contact.
Synonym(s): natural antibody.
References in periodicals archive ?
Polyreactive characteristics of natural antibodies against a variety of autoantigens have been proposed as an explanation for many functional aspects of this natural antibody (Satapathy and Ravindran, 1999).
During reperfusion, binding of natural antibody to N2 initiates the immune response and acute inflammation ultimately responsible for tissue damage in a broad range of conditions including myocardial infarction, stroke, burns, wound trauma and plastic surgery.
These researchers have managed to create a synthetic immune system in the test tube, as well as demonstrating its preventive and therapeutic potential due to exceeding the natural antibody repertoire the human body can generate.
Each mouse represents a 'DXL[TM] antibody factory' which combines the power of natural antibody diversity generation with the augmented potency of DXL[TM] technology.

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