natural antibody


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nor·mal an·ti·bod·y

antibodies occurring as a result of immunoglobulin DNA rearrangement and somatic hypermutation rather than in response to stimulation with a specific antigen.
Synonym(s): natural antibody

natural antibody

[nach′(ə)rəl]
Etymology: L, natura, nature; Gk, anti + AS, bodig, body
an antibody that is present in serum in the absence of an apparent specific antigen contact.

natural antibody

An antibody (e.g., anti-A, anti-B blood group antibodies) that is present in the circulation without prior exposure to the cognate antigen.

natural antibody

Normal antibody An antibody present in the circulation, without prior exposure to its cognate antigen

nor·mal an·ti·body

(nōr'măl an'ti-bod-ē)
Antibody demonstrable in the serum or plasma of various people or animals not known to have been stimulated by specific antigen, either artificially or as the result of naturally occurring contact.
Synonym(s): natural antibody.
References in periodicals archive ?
Polyreactive characteristics of natural antibodies against a variety of autoantigens have been proposed as an explanation for many functional aspects of this natural antibody (Satapathy and Ravindran, 1999).
Based on their findings, the researchers came to the conclusion that research into vaccines that mimic this natural antibody response may pay off.
In fact, antibody therapy is now available for a variety of situations in which natural antibody immunity is not likely to be effective, including prevention of re-stenosis after coronary angioplasty and the therapy for venomous animal bites, digitalis toxicity, breast cancer, and Crohn disease (reviewed in [77]).

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