naringin


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naringin

(nar'i-jin),
A bioflavonoid responsible for the bitter taste in grapefruit.
[Sansk. naringa, orange tree, + -in]

naringin

A flavanone glycoside and major flavonoid in grapefruit, which gives grapefruit juice its tangy/bitter taste. Naringin is metabolised in vivo to the flavanone naringenin.
 
Health benefits
Antioxidant activity; lowers serum lipid levels.

Alleged health benefits
Reduced risk of cancer; reduced neurologic residua following stroke.

Pharmacologic effects
Naringin inhibits certain cytochrome P450 enzymes (e.g., CYP3A4 and CYP1A2); it also inhibits vascular endothelial growth factor (VEGF) release, which induces angiogenesis.
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References in periodicals archive ?
Standardized to > 30% polyphenolic flavonoids, these compounds include naringin, neohesperidin, neoeriocitrin, 1% melitidine and 2% brutelidine, explained HP Ingredient's Ms.
The use of citrus bioflavonoids, which include rutin, quercetin, hesperidin, and naringin, has shown clinical results in the treatment of capillary permeability associated with allergic rhinitis.
Our study supports the previous studies that pH was not significant different in in vitro ruminal incubation with flavonoids such as flavone, myricetin, naringin, catechin, rutin, quercetin and kaempferol (Oskoueian et al.
Beneficial role of naringin, a flavanoid on nickel induced nephrotoxicity in rats.
The researchers gave one group of mice naringin, a bioactive compound in grapefruit juice that has been identified as a key agent in weight loss, and another group metformin, a glucose-lowering drug often prescribed for those with Type 2 diabetes.
Meanwhile, oranges are rich in several antioxidants, including hesperidin, naringin and tangeretin, which studies show may help to lower blood cholesterol.
A number of natural molecules such as non-polar coumarins (imperatorin and isoimperatorin), myricitrin, gossypin, quercetin, naringin, kaempferol, apigenin, hypericin, cardiospermin, chrysin, cinnamic acid, pcoumaric acid, caffeic acid, ferulic acid, sinapic acid, sanjoinine A, obovatol, magnolol, honokiol and linalool, isolated from plants have shown promising anxiolytic activity (Fernandez et al.
Naringin improves diet-induced cardiovascular dysfunction and obesity in high carbohydrate, high fat diet-fed rats.
1) Immensely rich in hesperidin and naringin, oranges are emerging as a weapon for boosting eye health, fighting heart disease, preventing kidney stones, and enhancing immunity.
flavanones including narirutin, naringin, neohesperidin) (Ortuno et al.
Bioflavonoids, like rutin and naringin, were proved beneficial as antioxidants particularly they were found useful in IR injury of other organs i.
Lower levels of naringin, which causes bitterness, mean the fruit is sweeter.