narcotic blockade

blockade /block·ade/ (blok-ād´)

1. the blocking of the effect of a hormone or neurotransmitter at a cell-surface receptor by a pharmacologic antagonist bound to the receptor.

2. in histochemistry, a chemical reaction that modifies certain chemical groups and blocks a specific staining method.

3. regional anesthesia.

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adrenergic blockade  selective inhibition of the response to sympathetic impulses transmitted by epinephrine or norepinephrine at alpha or beta receptor sites of an effector organ or postganglionic adrenergic neuron.

cholinergic blockade  selective inhibition of cholinergic nerve impulses at autonomic ganglionic synapses, postganglionic parasympathetic effectors, or the neuromuscular junction.

ganglionic blockade  inhibition by drugs of nerve impulse transmission at autonomic ganglionic synapses.

narcotic blockade  inhibition of the euphoric effects of narcotic drugs by the use of other drugs, such as methadone, in the treatment of addiction.

neuromuscular blockade  a failure in neuromuscular transmission that can be induced pharmacologically or may result from pathological disturbances at the myoneural junction.

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narcotic blockade

n.

The use of drugs to inhibit the effects of narcotic substances.

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blockade

1. in pharmacology, the blocking of the effect of a neurotransmitter or hormone by a drug.

2. in histochemistry, a chemical reaction that modifies certain chemical groups and blocks a specific staining method.

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adrenergic blockade

see adrenergic blockade.

cholinergic blockade

see cholinergic blockade.

narcotic blockade

inhibition of the euphoric effects of narcotic drugs by the use of other drugs, such as methadone, in the treatment of addiction.

sympathetic blockade

block of nerve impulse transmission between a preganglionic sympathetic fiber and the ganglion cell.