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a selective serotonin receptor agonist used as the hydrochloride salt in the acute treatment of migraine; administered orally.
naratriptan/nar·a·trip·tan/ (nar″ah-trip´tan) a selective serotonin receptor agonist used as the hydrochloride salt in the acute treatment of migraine.
An oral drug of the triptan class, C17H25N3O2S2, used in its hydrochloride form to treat migraine headaches.
a migraine agent.
indications It is used in the acute treatment of migraine with or without aura.
contraindications The following factors prohibit its use: angina pectoris, a history of myocardial infarction, documented silent ischemia, ischemic heart disease, concurrent use of ergotamine-containing preparations, uncontrolled hypertension, hypersensitivity, severe renal disease (creatinine clearance rate 15 mL/min), and severe hepatic disease in children (Pugh grade C).
adverse effects Adverse effects include nausea, myalgia, dizziness, sedation, and fatigue. Common side effects include weakness and neck stiffness.