nanophthalmia


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Related to nanophthalmia: nanophthalmos

nanophthalmos

 [nan″of-thal´mus]
abnormal smallness in all dimensions of one or both eyes in the absence of other ocular defects; see microphthalmos.

mi·croph·thal·mos

(mī'krof-thal'mos),
Abnormal smallness of the eye.
[micro + G. ophthalmos, eye]

nanophthalmia

/nan·oph·thal·mia/ (nan″of-thal´me-ah) nanophthalmos.

microphthalmia

A congenital reduction in eye size, with the ocular bulb measuring 1/2 of the normal volume in extreme cases, due to an abnormal development of the optic vesicle in the optic cup.

Aetiology
• Congenital—e.g., encephalo-ophthalmic dysplasia, focal dermal hypoplasia, Hallermann-Streiff syndrome, incontinentia pigmenti, Lenz microphthalmia syndrome, retinopathy of prematurity, trisomy 13-15.
• Infectious—e.g., CMV, herpes, rubella, toxoplasmosis.
• Toxins—e.g., foetal alcohol syndrome.

Incidence
14/105; 3–11% of all cases of blindness.

nanophthalmia

nanophthalmos.