naltrexone


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

naltrexone

 [nal-trek´sōn]
an opioid antagonist used as the hydrochloride salt in treatment of opioid or alcohol abuse.

nal·trex·one

(nal-treks'ōn),
An orally active narcotic antagonist; devoid of pharmacologic action when administered in the absence of narcotics.

naltrexone

/nal·trex·one/ (nal-trek´sōn) an opioid antagonist used as the hydrochloride salt in treatment of opioid or alcohol abuse.

naltrexone

(năl-trĕk′sōn)
n.
A synthetic opioid antagonist, C20H23NO4, used in its hydrochloride form to treat addiction to alcohol and to opioid drugs such as heroin.

naltrexone

Substance abuse An opioid antagonist used to manage opiate, alcohol and other abuse substances; naltrexone binds to endorphin receptors, preventing endophin receptor binding, reducing the craving for abuse substances. See Cocaine. Cf Antabuse.

naltrexone

A narcotic antagonist used as a maintenance therapy in former narcotic addicts. A brand name is Nalorex.

naltrexone (nal·trekˑ·sōn),

n a pharmacologic substance that increases the body's production of endorphins; used in treating narcotic addiction.

nal·trex·one

(nal-treks'ōn)
Orally active narcotic antagonist; devoid of pharmacologic action when administered in absence of narcotics.

naltrexone

an opiate antagonist similar to naloxone but with longer action and greater potency.
References in periodicals archive ?
A meta-analysis of observational clinical studies of patients treated with naltrexone found that those patients with the Asp40 allele were twice as likely not to relapse than were those who were homozygous for the Asn40 allele.
Whereas patients risk missing a dose with MMT, patients that receive a on naltrexone implant are more likely not to miss their daily dose of naltrexone as long as the implant is providing therapeutic levels until it completely dissolves months later
Acamprosate and oral naltrexone were comparably effective at reducing several measures of alcohol consumption.
The new meta-analysis combined findings from five other papers, comprising a total of 1,565 patients who received extended-release Naltrexone compared to other therapies for six months, among nearly 60,000 overall patients.
The aim of this study was to determine the frequency of anaesthesia-related adverse events in patients undergoing removal of naltrexone implants.
Naltrexone is an opiate antagonist that primarily blocks u-receptors with more variable occupancy of 8-receptors at the standard dose of 50 mg daily (Weerts et al.
Interestingly, a long-acting formulation of naltrexone available under the trade name Vivitrol is available but has not been utilized by clinicians as frequently as was expected.
At this time, low-dose naltrexone is only available from a compounding pharmacy by doctor's prescription.
A Welsh Assembly Government spokesman said: "The National Institute for Health and Clinical Excellence has looked at Naltrexone, but only in the context of opioid dependence, for which it is licensed.
Naltrexone is an opiate antagonist drug developed in the 1970s and approved by the FDA in 1984 for opiate and drug abuse treatment.
The naltrexone shots reduced the frequency of drinking days, the number of drinks and the percentage of days classed as heavy drinking sessions--5 or more drinks a day for men and 4 for women.
Importantly, naltrexone may be as effective when prescribed by physicians in primary care settings as in specialized treatment settings (O'Malley et al.