nalbuphine


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Related to nalbuphine: pentazocine

analgesic

 [an″al-je´zik]
1. relieving pain.
2. pertaining to analgesia.
3. an agent that relieves pain without causing loss of consciousness.
narcotic analgesic opioid analgesic.
nonsteroidal antiinflammatory analgesic (NSAIA) nonsteroidal antiinflammatory drug.
opiate analgesic (opioid analgesic) any of a class of compounds that bind with a number of closely related specific receptors (opioid receptors) in the central nervous system to block the perception of pain or affect the emotional response to pain; such compounds include opium and its derivatives, as well as a number of synthetic compounds, and are used for moderate to severe pain. Chronic administration or abuse may lead to dependence.

nalbuphine

/nal·bu·phine/ (nal´bu-fēn) an opioid analgesic, used as the hydrochloride salt in the treatment of moderate to severe pain and as an anesthesia adjunct.

nalbuphine

(năl-byo͞o′fēn′)
n.
A synthetic opioid narcotic, C21H27NO4, used in the form of its hydrochloride as an analgesic.

nalbuphine

a synthetic opioid agonist and antagonist.
indications This drug is used to treat moderate to severe pain.
contraindications Opiate addiction and known hypersensitivity to this drug prohibit its use.
adverse effects Adverse effects of this drug include dysphoria, hallucinations, dreaming, tolerance, physical dependency, psychological dependency, palpitations, bradycardia, change in blood pressure, orthostatic hypotension, tinnitus, blurred vision, miosis, diplopia, increased urinary output, dysuria, urinary retention, urinary urgency, urticaria, bruising, flushing, diaphoresis, pruritus, and pulmonary edema. Common side effects include drowsiness, dizziness, confusion, headache, sedation, euphoria, nausea, vomiting, anorexia, constipation, cramps, and rash. Respiratory depression is a life-threatening side effect.

nalbuphine

Nubain® A synthetic narcotic chemically related to naloxone and similar in action to, but less addictive than, morphine, it has a similar analgesic intensity as morphine, but has a ceiling on the intensity of the respiratory depression it causes when in excess Adverse effects Sweating, N&V, vertigo, dry mouth, headache

nalbuphine

a potent synthetic narcotic agonist-antagonist used as the hydrochloride for relief of moderate-to-severe pain.
References in periodicals archive ?
Alternatively, there seem to be fewer restrictions on obtaining and transporting the agonist/ antagonists such as butorphanol, dezocine, or nalbuphine.
Nalbuphine has both agonist and antagonist properties.
Leiken J, Barkin RL: Nalbuphine vs meperidine in sickle cell anemia DICP.
Nalbuphine ER, designed to be taken as a twice-daily tablet, uses Penwest's TIMERx(R) drug delivery technology.
The main objective of this Phase IIa study is to evaluate the analgesic efficacy of Nalbuphine ER in patients with chronic pain secondary to osteoarthritis of the knee or hip.
This increase was primarily due to increased spending on the development of nalbuphine ER and torsemide ER, as well as the stock-based compensation charge noted above.
today announced that it has begun a Phase I safety study on a nalbuphine hydrochloride extended release tablet formulation (Nalbuphine ER) that the Company is developing for the treatment of pain.
Nalbuphine ER is a controlled release formulation of nalbuphine hydrochloride that Penwest is developing using its TIMERx(R) drug delivery technology.
This increase was primarily due to increased spending on nalbuphine ER and torsemide ER, as well as the stock-based compensation charge noted above.
In particular, we are completing additional Phase I studies for nalbuphine ER and torsemide ER, and plan to advance both of these compounds into Phase II studies in 2007.
The increase is primarily due to increased spending on nalbuphine ER and the stock-based charge noted above.
The decrease was partially offset by the stock-based compensation charges noted above and increased spending on nalbuphine ER.