naked DNA


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.
A purified DNA sequence with no associated proteins. An immune response can be evoked by directly injecting into the host DNA that encodes an immunogen of interest

naked DNA

DNA that has been modified to remove the proteins that normally surround it. It is used for genetic transfers and vaccine manufacture.
See also: DNA
References in periodicals archive ?
Naked DNA delivery of angiogenic growth factors may be particularly attractive, since it provides prolonged production of the growth factor proteins at the site where they are needed, with a limited amount of protein escaping from that site.
Naked DNA is different from other gene-based delivery techniques because it doesn't use viruses to deliver the genetic material -- the genes are "virus-bare.
This patent effectively renews and reinforces Vical's previously issued patent covering naked DNA injection into muscle or skin to stimulate an immune response systemically.
Naked DNA is different from other gene delivery techniques because it doesn't use viruses to deliver the genetic material -- the genes are "virus-bare" or "naked.