naive


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naïve

 [nah-ēv´]
not previously exposed to therapy or treatment.

naive

or

naïve

(nī-ēv′, nä-) also

naif

or

naïf

(nī-ēf′, nä-)
adj.
Not having experienced or been subjected to something, as:
a. Not previously subjected to experiments: testing naive mice.
b. Not having previously taken or received a particular drug: patients naive to antipsychotic medication.

na·ive′ly adv.
na·ive′ness n.
Immunology Referring to a person or an immune system which has not been previously exposed to a particular antigen and thus doesn’t form antibodies against the antigen
Vox populi Innocent, unsophisticated, artless, ingenuous, unworldly, trusting

naive

in immunology, an individual that has not been exposed to a particular antigen.
References in periodicals archive ?
Art in naive cultures maintains its own circadian rhythm, greatly attuned to reproductive and seasonal patterns.
But serostatus of the naive partner is clearly important as well.
A&O argue that neither the conventional nor the generalized Phillips curve framework can do better than a simple forecast (their naive model) that says inflation over the coming year is expected to be the same as inflation over the past year.
Naive stem cells are blank slates that form the basis for not only all the cells of the human body, but cells that make up the placenta to support an embryo as well.
The table indicates that on roughly two out of every three occasions the Institute forecast for US GDP growth outperforms the naive forecast made with hindsight, with a similar margin over the feasible naive forecast.
Patient population plays a large part in this outcome and as discussed in an editorial by Aiuti and Giovannetti, (3) patients with good immunologic and virologic control, who were treatment naive before starting HAART and who are currently being treated with effective drug combinations, will probably have the best outcomes with STIs.
But when data on HSV-1- and HSV-2-seronegative partners were analyzed separately, the results were similar to the first study: The vaccine was ineffective among naive male partners and significantly effective (74%) among women in preventing genital herpes symptoms.
The majority of Arab architects also try to escape from naive layering but do not approve of high abstraction of tradition.
The global, dose-finding Phase 2 clinical program enrolled a total of 29 patients in three cohorts, including patients naive to eculizumab and patients with prior eculizumab exposure, including eculizumab switch patients and eculizumab inadequate responders.
New methods are being formulated to coax the "primed" ESCs--which more resemble cells from postimplantation embryos--back in time even more to resemble naive stem cells, those found in preimplantation embryos only days after fertilization.
The ability to derive naive stem cells has been possible for over thirty years from mouse embryos, using a technique developed at Cambridge, but this is the first time this has been possible from human embryos.
Janssen reported that in the first trial, known as OPTIMIST-1, the combination will be administered once daily for 8 or 12 weeks in chronic HCV genotype 1 infected patients without cirrhosis who are HCV treatment naive or treatment experienced.