nafcillin


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nafcillin

 [naf-sil´in]
a semisynthetic, acid- and penicillinase-resistant penicillin antibiotic effective against staphylococcal infections; administered orally or parenterally as the sodium salt.

nafcillin

/naf·cil·lin/ (naf-sil´in) a semisynthetic, acid- and penicillinase-resistant penicillin that is effective against staphylococcal infections; used as the sodium salt.

nafcillin

(năf′sĭl′ĭn)
n.
A semisynthetic penicillin, C21H22N2O5S, that is resistant to penicillinase, used in the form of its sodium salt primarily to treat infections caused by penicillinase-producing staphylococcus bacteria.

nafcillin

A semisynthetic penicillinase-resistant penicillin

nafcillin (nafsil´in),

n a semisynthetic penicillin designed as an antistaphylococcal penicillin. Also effective in the treatment of infections caused by pneumococci and Group A β-hemolytic streptococci.

nafcillin

a semisynthetic, acid- and penicillinase-resistant penicillin that is effective against staphylococcal infections. Used as the sodium salt.
References in periodicals archive ?
A number of drug-related adverse events occurred more often in 366 patients who received outpatient parenteral antimicrobial therapy (OPAT) with nafcillin, compared with 119 patients treated with cefazolin, including rash (13.
The manufacturer of the DxC 800 System (Beckman Coulter) lists nafcillin as an interferant; however, the interference mechanism is unknown (4).
With this approval, the Hyderabad-based company will be able to produce and sell the drug Nafcillin for injections which are needed to cure bacterial infections in the American market.
Aurobindo Pharma, an Indian pharmaceutical research company that manufactures and exportd drugs and formulations worldwide, has received approval to produce and market nafcillin, a sterile, semisynthetic penicillin, for injection USP from the US FDA, it was reported today.
John's wort 2C19 1A2 Substrates Citalopram Carbamazepine Clomipramine Clozapine Sertraline Olanzapine Valproic acid Inhibitors Cimetidine Amiodarone Fluoxetine Cimetidine Ketoconazole Fluoroquinolones Omeprazole Sertraline Valproic acid Inducers Carbamazepine Nafcillin Rifampin Phenobarbital Rifampin Smoking TCAs: tricyclic antidepressants Source: References 5,7,9
Penicillin resistant staphylococcus aureus should be treated with cloxacillin, nafcillin or methicillin.
Cultures grew methicillin-sensitive Staphylococcus aureus, and a prolonged course of nafcillin was started.
Nafcillin and voriconazole were added to the treatment regimen.
In the emergency department, blood and synovial fluid were obtained for culture, and the patient was empirically treated with intravenous nafcillin for septic arthritis.
However, these strain are susceptible to [beta]-lactam antibiotics such as methicillin or oxacillin and nafcillin.
With the bacteriophage test, a result indicating MSSA allows for the patient to be safely switched from empiric vancomycin to nafcillin or another conventional [beta]-lactam antibiotic, which are more effective against S.