myxedematous

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myx·e·dem·a·tous

(mik'sĕ-dem'ă-tŭs),
Relating to myxedema.

myx·e·dem·a·tous

(miks'ĕ-dem'ă-tŭs)
Relating to myxedema.
Synonym(s): myxoedematous.

myxedema

(mik-sĕ-dē′mă ) [ myx- + edema]
1. Infiltration of the skin by mucopolysaccharides, which give it a waxy or coarsened appearance and create nonpitting edema. Myxedematous skin is seen particularly in patients with hypothyroidism.
2. The clinical and metabolic manifestations of hypothyroidism in adults, adolescents, and children. myxedematous (-dem′ăt-ūs, -dēm′), adjective

Symptoms

The hypothyroid patient often complains of sluggishness, intolerance of cold, apathy, fatigue, and constipation. Findings may include infiltration of the subcutaneous layers of the skin by mucopolysaccharides. The hair may become dry and brittle. If the syndrome is left untreated, hypothermia, coma, and death may result.

Treatment

Thyroid hormone replacement reverses the symptoms and reestablishes normal metabolic function.

childhood myxedema

Myxedema occurring before puberty.

operative myxedema

Myxedema following removal of the thyroid gland.

pituitary myxedema

Myxedema occurring secondary to anterior pituitary hypofunction.

pretibial myxedema

Edema of the anterior surface of the legs following hyperthyroidism and exophthalmos.
References in periodicals archive ?
Concurrent iodine and selenium deficiency in children can destroy the thyroid gland, leading to the condition myxoedematous cretinism.
Selenium deficiency as a possible factor in the pathogenesis of myxoedematous endemic cretinism.
In contrast, myxoedematous cretinism is less common and characterised by dwarfism and mental deficits.