2] superfamily with high identity to Myotoxin
II from B.
3,4,7) Although federal and state health laboratories have not identified the heat-stable myotoxin
in Haff disease, mice fed samples of toxic buffalo fish developed histopathological evidence of rhabdomyolysis with renal tubular myoglobin and myoglobinuria.
It was found that myotoxin
probably causes renal damage due to myoglobin cast nephropathy.
Various other mechanisms have been suggested--directly acting cardiotoxin (5), myotoxin
causing cardiac muscle damage, (6) coronary vasospasm, (7) electrolyte disturbance, (8) severe hypotension (9) and disturbance of autonomic innervation of the heart.
Wedelolactone also antagonized the myotoxic activity in mice of venoms from Crotalus viridis viridis and Agkistrodon contortrix laticinctus and two phospholipase A2 myotoxins
, CVV myotoxin
and ACL myotoxin
, isolated from them .
8 Francis B, Gutierrez JM, Lomonte B, Kaiser II (1991) Myotoxin
II from Bothrops asper (terciopelo) venom is a ly sine-49 phospholipase Az.
A new muscle damaging toxin, myotoxin
II, from the venom of the snake Bothrops asper (terciopelo).
Inhibitor Proteins from Snakes, Mammals and Plants.
Natural phospholipase A(2) myotoxin
inhibitor proteins from snakes, mammals and plants.
The dynamics of local tissue damage induced by Bothrops asper snake venom and myotoxin
II on the mouse cremaster muscle: an intravital and electron miocroscopic study.
This plant represents a potential source of promising myotoxin
Leatherhead Food RA are co-ordinating the European Myotoxin
Awareness Network (EMAN), a European Commission funded project set up to combat lack of knowledge about this important safety issue.