myoglobinuria


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myoglobinuria

 [mi″o-glo″bin-u´re-ah]
the presence of myoglobin in the urine.

my·o·glo·bi·nu·ri·a

(mī'ō-glō'bi-nyū'rē-ă),
Excretion of myoglobin in the urine; results from muscle degeneration, which releases myoglobin into the blood; occurs in certain types of trauma (crush syndrome), advanced or protracted ischemia of muscle, or as a paroxysmal process of unknown etiology.

myoglobinuria

(mī′ə-glō′bə-no͝or′ē-ə)
n.
Excretion of myoglobin in the urine.

myoglobinuria

[-glō′binoo͡r′ē·ə]
Etymology: Gk, mys + L, globus + Gk, ouron, urine
the presence of myoglobin, an oxygen-storing pigment of muscle tissue, in the urine. The condition usually occurs after massive muscle injury, physical trauma, or electrical injury. The urine has a brown discoloration.

myoglobinuria

Internal medicine The loss of myoglobin in urine
Myoglobinuria, etiology  
Connective Tissue Disease Polymyositis, dermatomyositis
Hereditary Carnitine palmityl transferase deficiency, glycogen storage disease type V–phosphorylase deficiency, McArdle's disease, myopathies associated with glycogen or lipid storage, paroxysmal familial myoglobinuria, malignant hyperthermia, periodic paralysis
Infection
 Bacteria–eg, Legionnaire's disease
 Parasites–eg, trichinosis, toxoplasmosis
 Viral–eg, EBV, influenza, herpes
Toxins Alcohol–alcoholic myopathy, carbon monoxide, phencyclidine–PCP, 'angel dust', ethylene glycol, insect venom, some diuretics, Haff disease–historic interest
Trauma Crush injury, excess/prolonged physical exertion–eg, marathon running, severe muscle injury, crush injury
Etcetera Hyperthermia, infarction due to vascular occlusion, seizures
The diagnosis is based on clinical suspicion–especially with bright red urine and ↑ CK

my·o·glo·bi·nu·ri·a

(mī'ō-glō-bi-nyūr'ē-ă)
Excretion of myoglobin in urine; results from muscle degeneration, which releases myoglobin into the blood; occurs in certain types of trauma (e.g., crush syndrome), advanced or protracted ischemia of muscle, or as a paroxysmal process of unknown etiology.

myoglobinuria

The presence of MYOGLOBIN in the urine. This may occur when there is an excessive rate of breakdown of muscle (rhabdomyolysis) with release of myoglobin into the blood.

Myoglobinuria

Reddish urine caused by excretion of myoglobin, a breakdown product of muscle.

Meyer-Betz,

Friedrich, 20th century German physician.
Meyer-Betz disease - Synonym(s): Meyer-Betz syndrome
Meyer-Betz syndrome - excretion of myoglobin in the urine resulting from muscle degeneration. Synonym(s): Meyer-Betz disease; myoglobinuria

myoglobinuria

excretion of myoglobulin in urine, indicative of muscle tissue breakdown

myoglobinuria

the presence of myoglobin in the urine. It is evidence of severe muscle degeneration, though all such degenerations do not necessarily lead to myoglobinuria; it depends on the content of the pigment in the muscle and the renal threshold for it. The urine is red to dark red-brown, but in severe cases may be almost black.
Enlarge picture
Myoglobinuria in a horse with exertional myopathy. By permission from Knottenbelt DC, Pascoe RR, Diseases and Disorders of the Horse, Saunders, 2003

paralytic myoglobinuria
see paralytic myoglobinuria.
References in periodicals archive ?
Myonecrosis, myoglobinuria and acute renal failure induced by South American rattlesnake (Crotalus durissus terrificus) envenomation in Brazil.
The urine may be coffee coloured due myoglobinuria from acute muscle degeneration (13,27,30).
Rhabdomyolysis is a musculoskeletal condition characterised by muscle weakness, an elevated creatine kinase level and myoglobinuria.
In cases of severe muscle damage, creatine kinase and myoglobin from skeletal muscle cells will be released into the blood and myoglobinuria (Uberoi et al.
The urinalysis may show some evidence of systemic involvement (hemoglobinuria, myoglobinuria, hematuria).
The defects decrease energy production and lead to exercise intolerance, cramps, myoglobinuria, weakness in the muscles around the eye leading to droopy eyelids (ptosis), and external ophthalmoplegia (weakness of the eye muscles) (25).
Other consequences of PHS include worsened Parkinson's, deep vein thrombosis, disseminated intravascular coagulation, rhabdomyolysis, and renal failure resulting from myoglobinuria.
Azoturia (also known as paralytic myoglobinuria and equine exertional rhabdomyolysis) occurs most often in the physically fit horse whose ration is balanced to satisfy the nutrients needed during intense work.
Q We would like to discontinue offering the lab test for myoglobinuria.
The first clue for the presence of myoglobinuria is found in the urinalysis (UA) (Bonventre et al.
It is evidenced by extreme CK levels (12,542 U/L in this patient) , hyperkalemia, myoglobinuria, and acute renal insufficiency.