Stimulant laxatives: Bisacodyl, senna and dantron all act by stimulating the myenteric
nerve plexus of the gut, and possibly by direct action on the smooth muscle.
The area of the soma, cytoplasm, and the nucleus of 300 neurons of the myenteric
plexus of the terminal ileum and the descending colon (uniformly distributed all over the intestinal circumference) of the animals from each group was measured with the software Image Motic Plus, version 2.
The role of the myenteric
plexus in the Schistosoma-induced alterations of GI motility remains an enigma.
They have been found in the peripheral nervous system such as myenteric
and submucosal neurons (Glatzle et al.
In previous studies, neuronal NOS (nNOS) has been identified in enteric nerve terminals and concentrated in the longitudinal muscle layer with attached myenteric
plexus (Huber et al.
Some chemotherapeutic agents also damage the myenteric
plexus, leading to motility problems.
Virus antigen expression was found in neurons and satellite cells in the peripheral nervous system (submucosal and myenteric
plexi, mesenteric ganglia) of the small intestine (online Appendix Figure 4, panel A, available from www.
17) Abnormalities of the colonic myenteric
plexus in STC might be another explanation for the impaired response of the gallbladder to modified sham feeding.
4] receptors are known to facilitate ACh release at the myenteric
neurons and nerve terminals of GI tracts, followed by producing the smooth muscle contractions (Chetty et al.
Within the small intestine and cecum, the strongest and most consistent immunolabeling involved the parasympathetic ganglia of the submucosal and myenteric
plexi (Figure 1, panel D) with only the occasional scattered smooth muscle and vascular endothelial cell within the gut mucosa positive for viral antigen.
A significant proportion of studies have found degeneration of neurons in the myenteric
plexus in severe idiopathic constipation (5,26) and in STC.
Hirschsprung disease (HD) is characterized histologically by the absence of autonomic ganglion cells in the myenteric
and submucosal plexuses and by the presence of hypertrophied nerve trunks in the space normally occupied by the ganglion cells in the terminal bowel.