myeloproliferative disorder


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myeloproliferative disorder

A hematopoietic stem cell disease. Cf Lymphoproliferative disorder.
Myeloproliferative disorder
Acute MPD Acute myelogenous leukemia–myeloblastic, promyelocytic, myelomonocytic, monocytic, erythroid, megakaryocytic, eosinophilic, basophilic, acute biphenotypic–with myeloid and lymphoid markers, leukemia, and acute leukemia with lymphoid markers evolving from a prior clonal hemopathy
Subacute MPD Oligoblastic–smoldering leukemia, refractory anemia with excess blasts–see RAEB, myelomonocytic leukemia.
Chronic MPD Polycythemia vera, agnogenic myeloid metaplasia, primary thrombocythemia, chronic myelogenous leukemia–Philadelphia chromosome positive or negative, chronic monocytic leukemia, chronic neutrophilic leukemia  

myeloproliferative disorder

Any of several hematologic malignancies marked by the excessive multiplication of one or more types of blood cells. These disorders include polycythemia rubra vera, essential thrombocytosis, chronic myeloid leukemia, and idiopathic myelofibrosis.

Myeloproliferative disorder

A disorder in which the bone marrow produces too many cells too rapidly.
Mentioned in: Polycythemia Vera
References in periodicals archive ?
28] Their patient developed lytic lesions of the tibia and was classified and treated as chronic eosinophilic leukemia, a myeloproliferative disorder, rather than HES or atypical CML.
Hydroxyurea treatment has not yet been associated with a significant increase in myeloblastic transformation in myeloproliferative disorders, but its myelotoxic effects could have contributed to the worsening hematological status and myelofibrosis in this patient (7), (8).
18% of men in a cohort of patients seen at the center for myeloproliferative disorders of Johns Hopkins University in Baltimore, said Dr.
Acute leukemia and the transient myeloproliferative disorder associated with Down syndrome: morphologic, immunophenotypic and cytogenetic manifestations.
For over 50 years, HU has been used in the treatment of chronic myeloproliferative disorders, such as chronic myeloid leukemia, polycythemia vera, and ET (3).
Platelet counts >1000 K/[micro]L are not unusual in a general hospital population (1); however, such extreme numbers are encountered more commonly in myeloproliferative disorders or after splenectomy (4).
Loeffler endocarditis causing calcification can be related to myeloproliferative disorder.
A 72-year-old white man first presented in September 1992 with a suspected myeloproliferative disorder.
In general, patients with a myeloproliferative disorder often have platelet counts greater than 1 X [10.
Fruchtman held faculty positions at Mount Sinai Hospital where, over that time, he served as director of the Myeloproliferative Disorder Program, Clinical Director of the Division of Hematology, Stem Cell Transplantation Service, Hematology Fellowship Training Program, Sickle Cell Program and Mount Sinai Hematology Faculty Practice Associates.
The IG parameter provides detection and quantification of circulating immature granulocytes that may be used as an early indicator of acute infection, inflammatory response, or myeloproliferative disorder.