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myeloproliferative

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myeloproliferative /my·elo·pro·lif·er·a·tive/ (-pro-lif´er-ah-tiv) pertaining to or characterized by medullary and extramedullary proliferation of bone marrow constituents; see under disorder.
my·e·lo·pro·lif·er·a·tive (m-l-pr-lf-rtv)
adj.
Relating to or characterized by unusual proliferation of myelopoietic tissue.

myeloproliferative [mi″ĕ-lo-pro-lif´er-ah″tiv]
pertaining to or characterized by abnormal proliferation of bone marrow constituents.
myeloproliferative disorders a group of usually neoplastic diseases, which may be related histogenetically by a common multipotential stem cell; it includes among others acute myelogenous leukemia, chronic granulocytic leukemia, acute and chronic myelomonocytic leukemias, and polycythemia vera. An interrelationship with the lymphoproliferative disorders is thought to exist.

myeloproliferative
pertaining to or characterized by abnormal proliferation of bone marrow constituents.

myeloproliferative disease
a group of diseases related histogenetically and marked, at varying times in varying degrees, by medullary and extramedullary proliferation of one or more lines of bone marrow constituents, including myelocytic, erythroblastic and megakaryocytic forms, in addition to various cells derived from the reticulum and mesenchymal elements. It occurs most commonly in cats, often associated with feline leukemia virus infection, causing anemia, weight loss, fever and hepatosplenomegaly. Hematological findings usually include the presence of abnormal cells, corresponding to the proliferating cell type. The forms seen include erythremic myelosis, reticuloendothelosis, myeloid leukemia, erythroleukemia, monocytic leukemia, myelomonocytic leukemia, megakaryocytic myelosis and eosinophilic leukemia.


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Cytopia is continuing to build on its range of JAK inhibitors and kinase expertise, with CYT387, a novel oral JAK2 inhibitor focused on the treatment of myeloproliferative disorders, expected to enter Phase I clinical studies in 2009.
After 6 to 12 months of transplantation, the expansion led to the development of a myeloproliferative disease, which can evolve to leukaemia.
I've got a strange myeloproliferative disorder which the doctors have never really come across before and have never quite known what to do with.
 
 
 
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