myelophthisis


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myelophthisis

 [mi″ĕ-lo-thi´sis]
1. wasting of the spinal cord.

my·e·loph·thi·sis

(mī'ĕ-lof'thi-sis, mī'ĕ-lō-tī'sis, -tē'sis),
1. Wasting or atrophy of the spinal cord as in tabes dorsalis.
2. Replacement of hematopoietic tissue in the bone marrow by abnormal tissue, usually fibrous tissue or malignant tumors that are most commonly metastatic carcinomas. Synonym(s): panmyelophthisis
[myelo- + G. phthisis, a wasting away]

myelophthisis

/my·e·loph·thi·sis/ (mi″ĕ-lo-thi´sis)
1. wasting of the spinal cord.
2. bone marrow suppression secondary to marrow infiltration by tumor with local production of myelosuppressive cytokines.

panmyelophthisis

(1) Bone marrow replacement by native or non-native cells (e.g., myeloma, metastatic malignancy), fibrosis or inflammation.
(2) Aplastic anaemia, see there.

my·e·loph·thi·sis

(mī'ĕ-lof'thi-sis)
1. Wasting or atrophy of the spinal cord as in tabes dorsalis.
2. Replacement of hemopoietic tissue in the bone marrow by abnormal tissue, usually fibrous tissue metastatic carcinomas.
Synonym(s): panmyelophthisis.
[myelo- + G. phthisis, a wasting away]

my·e·loph·thi·sis

(mī'ĕ-lof'thi-sis)
Wasting or atrophy of the spinal cord. Replacement of hemopoietic tissue in the bone marrow by abnormal tissue.
Synonym(s): panmyelophthisis.
[myelo- + G. phthisis, a wasting away]

myelophthisis (mī´əlōfthī´sis),

n a displacement of bone marrow by fibrous tissue, carcinoma, or leukemia.
Enlarge picture
Myelomeningocele.

myelophthisis

1. wasting of the spinal cord.
2. reduction of the cell-forming functions of bone marrow.
References in periodicals archive ?
The right pelvic limb lameness could have been caused by bone pain secondary to myelophthisis, although other causes, such as trauma resulting from generalized weakness, cannot be ruled out.
The mild anemia and the thrombocytopenia could have been caused by myelophthisis or chlorambucil toxicity, although heteropenia would likely also be expected in these instances.
Myelophthisis as a solitary manifestation of failure in rectal cancer may be an extreme and rare example of the Batson phenomenon in rectal cancer metastases, but it draws renewed attention to the experimentally established validity and clinical implications of this mode of spread in pelvic neoplasms.