myelokathexis


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ka·thex·is

(kă-theks'is),
A rare disorder characterized by bone marrow retention of myeloid elements leading to severe peripheral neutropenia; neutrophils have a distinctly abnormal appearance; Gm-CSF levels are undetectable and administration of this substance is therapeutically effective.
Synonym(s): myelokathexis

ka·thex·is

(kath-eks'is)
A rare disorder characterized by bone marrow retention of myeloid elements leading to severe peripheral neutropenia; neutrophils have a distinctly abnormal appearance; granulocyte-macrophage colony-stimulating factor levels are undetectable and administration of this substance is therapeutically effective.
Synonym(s): myelokathexis.

myelokathexis

(mī″ĕ-lō-kă-thek′sĭs) [ myelo- + cathexis]
A congenital form of neutropenia in which mature granulocytic white blood cells are not released from the bone marrow to circulate in the bloodstream. It is often inherited as an autosomal dominant condition associated with warts, low levels of gamma globulins, and recurrent infections (WHIM syndrome).

myelokathexis

neutropenia resulting from bone marrow retention in the face of adequate reserves.
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