myeloencephalitis


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myeloencephalitis

 [mi″ĕ-lo-en-sef″ah-li´tis]
inflammation of the spinal cord and brain.

myeloencephalitis

/my·elo·en·ceph·a·li·tis/ (-en-sef″ah-li´tis) inflammation of the spinal cord and brain.

myeloencephalitis

(mī″ĕl-ō-ĕn-sĕf″ă-lī′tĭs) [″ + ″ + itis, inflammation]
Inflammation of the spinal cord and the brain.

myeloencephalitis

inflammation of the spinal cord and brain. See also encephalomyelitis

equine herpesvirus myeloencephalitis
caused by some strains of equine herpesvirus 1. The lesions differ from other herpesvirus encephalidities in other species in that there are thrombi in small blood vessels, probably caused by viral antigen-antibody complexes and consequent anoxic changes, including loss of neurons. Called also equine herpesvirus encephalomyelitis.
equine protozoal myeloencephalitis (EPM)
presents with focal or multifocal signs of neurologic disease involving the brain, brain stem and or spinal cord. It is caused most commonly by Sarcocystis neurona but occasionally by Neospora caninum or the closely related N. hughesi. The definitive host for S. neurona in North America is the North American possum Didelphis virginiana and in South America D. marsupialis and D. albiventris. The disease is more common in the summer, may be acute or chronic, and there is great variation in clinical signs due to the ability of the organism to infect both white and gray matter at multiple sites in the central nervous system.
References in periodicals archive ?
Clinical and epidemiological characteristics of 162 patients with myeloencephalitis probably caused by Gnathostoma spinigerum.
Two fatal cases of eosinophilic myeloencephalitis a newly recognized disease caused by Gnathostoma spinigerum.
In vitro cultivation and characterization of a Neospora isolate obtained from a horse with protozoal myeloencephalitis.
Interpreting immunoblot testing of cerebrospinal fluid for equine protozoal myeloencephalitis.
Nitazoxanide is a product for the treatment of equine protozoal myeloencephalitis (EPM).
EHV-1 is endemic in domestic horses and can cause pneumonia, myeloencephalitis, and abortion (13).
ANOTHER top Kentucky stallion, Woodman, is covering again after undergoing precautionary treatment for the bacterial disorder equine proto- zoal myeloencephalitis (EPM).
IDEXX Pharmaceuticals also has a number of products in the registration process with the FDA, including a nitazoxanide-based product for treatment of equine protozoal myeloencephalitis -- a neurological disease that is believed to affect approximately 200,000 horses in the US; a topical non-steroidal anti-inflammatory for equine use; an insulin product for the treatment of diabetic cats; and a long-acting injectable antibiotic for cats are also in development.
Several neurologic conditions were considered in the differential diagnosis, including other viral encephalomyelitides (rabies, Aujesky disease, Borna disease, EHV-1 myeloencephalopathy, WEEV, and WNV encephalomyelitis), bacterial meningitis, listeriosis, leukoencephalomalacia, lead poisoning, equine protozoal myeloencephalitis, nigropallidal encephalomalacia, botulism, and verminous encephalitis.
Food and Drug Administration has informally told the Company that it is likely to issue an incomplete letter regarding the Company's new animal drug application (NADA) for nitazoxanide, a drug intended for the treatment of equine protozoal myeloencephalitis.
The Company is seeking FDA approval of a number of other drugs for companion animals, including a treatment for equine protozoal myeloencephalitis (EPM), a non-steroidal anti-inflammatory, and a novel, long-acting antibiotic for companion animals.
The new company is a leading-edge veterinary biotechnology company whose first product is the world's only reliable test for equine protozoal myeloencephalitis (EMP), which causes severe damage to horses' central nervous systems.