myelodysplasia


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myelodysplasia

 [mi″ĕ-lo-dis-pla´zhah]
1. a neural tube defect consisting of defective development of part of the spinal cord. See also spina bifida.
2. dysplasia of myelocytes and other elements of the bone marrow, a chronic disease that in time may evolve into acute myelogenous leukemia. adj., adj myelodysplas´tic.

my·e·lo·dys·pla·si·a

(mī'ĕ-lō-dis-plā'zē-ă),
1. An abnormality in development of the spinal cord, especially the lower part of the cord.
2. Inappropriate term for spina bifida occulta.
Synonym(s): myelodyspoiesis
[myelo- + G. dys-, difficult, + plasis, a molding]

myelodysplasia

/my·elo·dys·pla·sia/ (-dis-pla´zhah)
1. a neural tube defect causing defective development of any part of the spinal cord.
2. dysplasia of myelocytes and other elements of the bone marrow.myelodysplas´tic

myelodysplasia

(mī′ə-lō-dĭs-plā′zhə)
n.
1. Abnormal development of the spinal cord.
2. Dysplasia of myelocytes and other cells in the bone marrow.

my′e·lo·dys·plas′tic (-plăs′tĭk) adj.

myelodysplasia

[mī′əlōdisplā′zhə]
Etymology: Gk, myelos + dys, bad, plassis, formation
1 a general designation for the defective development of any part of the spinal cord. The term is used primarily to describe abnormalities without gross superficial defects, especially of the lower segment, specifically spina bifida occulta.
2 dysplasia of the myelocytes and other elements in bone marrow.

myelodysplasia

Hematology Abnormal BM precursor cells, which may lead to CML. See Myelodysplastic syndrome Neurology A generic term for various developmental defects of the spinal cord and nerve roots–eg, myelomeningocele, sacral agenesis, spinal dysraphism and caudal regression syndrome;13 of infants with myelodysplasia develop external urethral sphincter dysfunction, often in the first 3 yrs of life, 12of which are permanent.

my·e·lo·dys·pla·si·a

(mī'ĕ-lō-dis-plā'zē-ă)
1. An abnormality in development of the spinal cord, especially the lower part of the cord.
2. A disorder within the bone marrow, characterized by the proliferation of abnormal stem cells, which have the potential of developing into a specific type of leukemia.
[myelo- + G. dys-, difficult, + plasis, a molding]

myelodysplasia

See MYELODYSPLASTIC SYNDROME.

myelodysplasia

1. defective development of the spinal cord.
2. disorders of myeloid cells of the bone marrow, either in number or degree of maturity.

hemopoietic myelodysplasia
includes myeloid metaplasia and myelofibrosis, refractory anemia with excess blast cells, and myelomonocytic leukemia.
myelodysplasia syndrome
qualitative defect in stem cells characterized by dysplastic hematopoietic cells and the presence of abnormal blast cells in the blood. There is also anemia, leukopenia and sometimes thrombocytopenia. See also myeloproliferative disease.
References in periodicals archive ?
While his area of major expertise is bacterial infection and sepsis, he has also researched myelodysplasia, myeloproliferative neoplasms, acute leukemias, vitamin B12 and folate deficiencies, dengue fever, and malaria, among other topics.
6] In children with myelodysplasia, there are two RCTs[sup.
Since then the incidence of myelodysplasia and neural tube defects has fallen dramatically.
Patients with acquired amegakaryocytic thrombocytopenia may have additional hematological abnormalities such as macrocytosis or dyserythropoiesis, abnormalities which may indicate potential future progression to aplastic anemia or myelodysplasia (8-10).
16-19) In 18 patients (33 clubfeet) with myelodysplasia, who were treated with casts and percutaneous Achilles tenotomies (PATs), 31 feet required no further treatment; the remaining two had posterior medial releases to correct recurrences.
Margaret's inspiration for the charity came about when her father, Brian Kirby, 69, was diagnosed with myelodysplasia, which destroys the immune system, giving sufferers little chance to fight minor complaints.
Emma was diagnosed with a rare blood condition known as myelodysplasia - where the bone marrow stops producing healthy cells and which normally affects those aged over 60.
died in June after a six-year battle with myelodysplasia (bone marrow cancer) and a 40-year battle with a rare neurodegenerative disease.
Genetic pathways in the pathogenesis of therapy-related myelodysplasia and acute myeloid leukemia.
Until recently myelodysplasia was not considered to be a form of cancer, and therefore [was] not tracked by our registries," Dr.
Myelodysplasia or acute myelogenous leukemia was observed in 2 percent of patients (8 to 34 months after treatment).