mycobacterium simiae

mycobacterium simiae

A mycobacterium, first isolated from rhesus macaques in 1965. It is a slow-growing photochromogen, appearing rust-coloured after exposure to light, and is the only nontuberculous mycobacterium that, like M tuberculosis, is niacin positive. Most isolates of M simiae have been reported from the southwestern US, Cuba and Israel. Its environmental niche is believed to be aquatic.

Clinical finding
M simiae infection most commonly occurs in HIV-positive patients with pulmonary disease as well as lymphadenopathy, skin lesions and genitourinary tract involvemen. M simiae may cause infection (e.g., regional lymphadenopathy) in immunocompetent hosts.

Management
Isoniazid, rifampin, ethambutol.

My·co·bac·te·ri·um sim·i·ae

(mī'kō-bak-tēr'ē-ŭm sim'ē-ē)
A slow-growing, photochromogenic, acid-fast bacillus; rarely associated with pulmonary disease in humans.
References in periodicals archive ?
1,3,4) Other species that have been documented in birds include Mycobacterium tuberculosis, Mycobacterium fortuitum, Mycobacterium gordonae, Mycobacterium nonchromogenicum, Mycobacterium simiae, and Mycobacterium peregrinum.
Infection with Mycobacterium simiae complex in four captive Micronesian kingfishers.
Characterization of mycobacterial isolates phylogenetically related to, but different from Mycobacterium simiae.
Among 68 patient episodes of mycobacteremia identified by Myco/F Lytic culture during a 10-year period from 1997 through 2006, there were 59 patients with Mycobacterium avium complex; 6 with Mycobacterium tuberculosis complex; and 3 with Mycobacterium abscessus, Mycobacterium simiae, and coinfection with M avium complex and M kansasii, respectively.
Mycobacterium simiae outbreak associated with a hospital water supply.
Disseminated Mycobacterium simiae infection in patients with AIDS.
Successful treatment of disseminated Mycobacterium simiae infection in AIDS patients.
Pulmonary and disseminated Mycobacterium simiae infection in humans.
Clinical isolates of Mycobacterium simiae in San Antonio, Texas.
Characterization of mycobacteria isolates phylogenetically related to, but different from Mycobacterium simiae.
By using restriction endonuclease analysis of the 65-kDa heat shock protein gene (1), we found that the isolate showed a pattern compatible with Mycobacterium simiae.
Mycobacterium simiae pseudo-outbreak resulting from a contaminated hospital water supply in Houston, Texas.

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