mutagenicity


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Related to mutagenicity: mutagenesis

mutagenicity

 [mu″tah-jĕ-nis´ĭ-te]
the property of being able to induce genetic mutation.

mutagenicity

/mu·ta·ge·nic·i·ty/ (-jĕ-nis´it-e) the property of being able to induce genetic mutation.

mutagenicity

The ability of a chemical or physical agent to cause permanent changes in DNA.

mutagenicity

the property of being able to induce genetic mutation.
References in periodicals archive ?
Benchmark Data Set for in Silico Prediction of Ames Mutagenicity.
cytochrome P450, lessens almost completely the mutagenicity of the extracts of chlorinated waters.
Role of mutagenicity in mineral fiber-induced carcinogenicity and other diseases.
46] Umbuzeiro GD, Roubicek DA, Sanchez PS and Sato MIZ (2001) The Salmonella mutagenicity assay in a surface water quality monitoring program based on a 20-year survey.
The effect of flavonoids on ofloxacin-induced mutagenicity in Euglena gracilis.
coli tester strains recommended by regulatory agencies and evaluates colony formation, cytotoxicity and compound precipitation using an agar format, factors that make this screen the most predictive mutagenicity screen for the regulatory GLP Ames assay - a claim no other company can make.
Big Blue is identified in OECD Test Guideline 488, as well as recommended by various agencies and expert groups, including the European Chemicals Agency, as an accepted assay for evaluating mutagenicity in somatic and male germ cell tissues.
Sarah Nexus combines our expertise in mutagenicity with novel machine-learning algorithms to provide predictions that are supported by estimates of accuracy, clear explanations of how they are derived and direct access to the underlying supporting data.
KEY WORDS: Ames assay, carcinogenicity, 21st century toxicology, genetic toxicology, high-throughput assays, Salmonella assay, Salmonella mutagenicity assay.
DBM has been reported to antagonize the mutagenicity of several chemical carcinogens in vitro and has recently been shown to be even more effective than curcumin in suppressing the 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumors in rats.
Scientists use mutagenicity -- the ability to cause genetic mutation -- as a rough gauge of potential carcinogenicity.