mutagenesis


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mutagenesis

 [mu″tah-jen´ĕ-sis]
the induction of genetic mutation.

mu·ta·gen·e·sis

(myū'tă-jen'ĕ-sis),
1. Production of a mutation.
2. Production of genetic alteration through use of chemicals or radiation.

mutagenesis

/mu·ta·gen·e·sis/ (mu″tah-jen´ĕ-sis)
1. the production of change.
2. the induction of genetic mutation.

mutagenesis

(myo͞o′tə-jĕn′ĭ-sĭs)
n.
Formation or development of a mutation.

mutagenesis

[myo̅o̅′təjen′əsis]
the induction or occurrence of a genetic mutation. See also teratogenesis.

mu·ta·gen·e·sis

(myūtă-jenĕ-sis)
1. Production of genetic alterations by using chemicals or radiation.
2. Production of a mutation.

mutagenesis

any process that brings about MUTATION in vivo or in vitro. See MUTAGEN, OLIGONUCLEOTIDE MUTAGENESIS, SITE DIRECTED MUTAGENESIS, TRANSPOSABLE GENETIC ELEMENT.

mu·ta·gen·e·sis

(myūtă-jenĕ-sis)
1. Production of a mutation.
2. Production of genetic alteration through use of chemicals or radiation.

mutagenesis,

n the induction or occurrence of a genetic mutation.

mutagenesis

the process of inducing genetic mutation.

site directed mutagenesis
a set of methods used to experimentally create specific changes in the nucleotide sequence of a gene.
References in periodicals archive ?
Transposon-mediated reporter gene mutagenesis has been used extensively in the field of bacterial pathogenesis to identify loci upregulated by mammalian body temperature and other environmental cues such as calcium concentration (4).
Site-specific mutagenesis played an important role in the solution of the structure in that the cysteine mutants C865, C1 14S, and C173S were used to help locate the positions of heavy atoms and to align the sequence with the model derived from the experimental phases.
Ixsys' Directed Evolution technology is centered around the Kauffman and Codon-Based Mutagenesis (CBM) patents, which form the foundation of the company's broad discovery and protein engineering capabilities.
The currently prominent approach, generation of novel serotypes from the known cardiotropic ones (AAV6 and 9) by random mutagenesis, alters favorable serotype attributes and most importantly tropism.
com)-- Creative BioMart, a world leading Biotech Company, has conducted a morning talk to discuss its mutagenesis.
Using APOBEC's distinctive DNA mutational signature, the team of researchers examined approximately 1 million mutations in 2,680 cancer samples, and found that, in some tumors, nearly 70 percent of mutations in a given specimen resulted from APOBEC mutagenesis.
Transposagen's project titled: Creation of Hyperactive Transposons for Mutagenesis in Rodents will further develop Transposagen's piggyback (TM) DNA Modification System.
Palmitoylation of DAT by PAT enzymes will be confirmed by site-directed mutagenesis of DHHC enzymes to determine the specificity, followed by analysis of palmitoylation effects on DAT function.
Among their perspectives are inhibiting HIV entry, helicase-primase inhibitors as a new approach to combating herpes simplex virus and varicella zoster virus, alkoxyalkyl ester pro-drugs of antiviral nucleoside phosphate and phosphonates, maribavir as a novel benzimidazole ribonucleoside for preventing and treating cytomegalovirus diseases, lethal mutagenesis as an unconventional approach to combating HIV, silencing viruses with antiviral RNAi, and neuraminidase inhibitors as anti-influenza agents.
Smaller projects designed to develop novel techniques, such as strategies for mutagenesis, conditional gene expression, or for identifying new genes or mutants, as well as new tools to mine and analyze sequence data:
The utility of this vector lies in its ability to isolate, manipulate and maintain large fragments in bacteria and yeast, allowing for mutagenesis by yeast genetics and simplified preparation of plasmid DNA in bacteria.
Mutagenesis and cell transformation in cell culture.