In the present study elenoside was given to rats at doses of 25 and 50 mg/kg, and its effects on locomotor activity (Varimex test), muscular relaxant
activity, open-field test and with chlorpromazine, 10 mg/kg was compared.
This acts as a muscular relaxant
, reducing tension and spasm, as well as easing anxiety and nervous overactivity.
Yasunobu Handa, a part-time doctor at the hospital in Sendai in Miyagi Prefecture, northeastern Japan, believed the sudden changes in the patients' conditions were due to their intravenous drips being laced with muscular relaxant
by Mori, the prosecutors said.
When ZEMURON (rocuronium bromide) is administered to these patients, shorter durations of neuromuscular block may occur, and infusion rates may be higher due to the development of resistance to non-depolarizing muscular relaxants