muscle metabolism


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Related to muscle metabolism: creatinine

muscle metabolism

The consumption of energy by all cells, including those of muscle tissue, to perform work. The source of chemical energy, adenosine triphosphate (ATP), is metabolized to adenosine diphosphate (ADP). If the energy requirement is short-term, the ADP is converted back to ATP. This process is too slow to keep up with energy demands during long-term exercise; thus, consumption of other fuels is required. The main sources of fuel for muscles are carbohydrates and lipids. Before being available for intracellular metabolism, glycogen is obtained when glucose is converted to glycogen. The main lipid fuel is free fatty acids present in plasma. Carbohydrates can be metabolized either in the presence of oxygen (aerobically) or in its absence (anaerobically), but lipids can be metabolized only aerobically. During light exercise or when the body is at rest, muscle metabolism is usually entirely aerobic, and the source of fuel is the free fatty acids in plasma. During intense exercise, metabolism of the fatty acids cannot keep up with the demand, and glycogen is used for energy. However, as intense exercise continues, glycogen stores are exhausted, and free fatty acids become the principal source of energy. Trained athletes have an increased ability to metabolize fatty acids as compared with sedentary people; this permits athletes to exercise longer and at higher work rates than untrained people. Athletic trainers have found that muscle glycogen stores can be increased by carbohydrate loading.
Working articulation.
See also: metabolism
References in periodicals archive ?
The mitochondrial changes that occur due to endurance training have important effects on skeletal muscle metabolism during submaximal exercise, all of which help to improve performance (1), (3), (6).
Exercise can reduce TNF-[alpha] and improve skeletal muscle metabolism and systemic insulin sensitivity [75].
The older rodents also scored as well as the younger rats on measures of muscle metabolism.
Hagerty joins MDA from GlaxoSmithKline, where she was as an investigator within its Skeletal Muscle Metabolism Discovery Unit.
This is a by-product of muscle metabolism and is filtered out of the body by the kidney, known as the glomerular filtration rate or GFR.
Effect of preslaughter anesthesia on muscle metabolism and meat quality of pigs of different halothane genotypes.
Impact of exercise intensity on body fatness and skeletal muscle metabolism.
Several major gene categories or clusters are differentially expressed between the paretic and nonparetic leg muscles, including genes that regulate muscle metabolism, contractile proteins, cell cycle progression, mitogenesis and growth factors, metabolism, inflammation, and signal transduction pathways.
In view of the fact that frailty was defined mostly by sarcopenia, the investigators concluded that insulin resistance, inflammation, and frailty are all related to a primary disorder of muscle metabolism.
Endurance athletes use an entirely different type of muscle metabolism than dancers.
Hence, muscle metabolism in females is mostly independent of circulating sex hormones, in contrast to men.