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muscarinic
(redirected from muscarinic blocking agents)

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muscarinic /mus·ca·rin·ic/ (mus″kah-rin´ik) denoting the cholinergic effects of muscarine on postganglionic parasympathetic neural impulses.
muscarinic
[mus′kərin′ik]
Etymology: L, musca, fly
1 stimulating the postganglionic parasympathetic receptor.
2 pertaining to the poisonous activity of muscarine.

muscarinic
pertaining to the transmission of nerve impulses mediated by muscarinic receptors; these may be adrenergic or cholinergic.

muscarinic activity
includes slowing and reduced stroke volume of the heart, bronchiolar constriction, arteriolar dilatation, increased tone, motility and secretion in the alimentary tract, and increases in salivation and lacrimation.
muscarinic blocking agents
block muscarinic receptors, e.g. atropine and the synthetic agents homatropine, methantheline, propantheline and methylatropine.
muscarinic receptors
cholinergic receptors of autonomic effector cells (and also on some autonomic ganglion cells and some central neurons) that are stimulated by muscarine and parasympathomimetic drugs and antagonized by atropine.


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