muscarinic


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mus·ca·rin·ic

(mŭs'kă-rin'ik),
1. Having a muscarinelike action, that is, producing effects that resemble postganglionic parasympathetic stimulation.
See also: muscarine, nicotinic.
2. An agent that stimulates the postganglionic parasympathetic receptor.
See also: muscarine, nicotinic.

muscarinic

/mus·ca·rin·ic/ (mus″kah-rin´ik) denoting the cholinergic effects of muscarine on postganglionic parasympathetic neural impulses.

muscarinic

[mus′kərin′ik]
Etymology: L, musca, fly
1 stimulating the postganglionic parasympathetic receptor.
2 pertaining to the poisonous activity of muscarine.

mus·ca·rin·ic

(mŭs'kă-rin'ik)
1. Having a muscarinelike action, i.e., producing effects that resemble postganglionic parasympathetic stimulation.
2. An agent that stimulates the postganglionic parasympathetic receptor.
See also: muscarine, nicotinic

muscarinic

1. Producing the effects of post-ganglionic cholinergic stimulation of the parasympathetic. Having an effect similar to that of the mushroom poison MUSCARINE.
2. Of an acetylcholine receptor that responds to muscarine. Compare NICOTINIC.

muscarinic

(in physiological terminology) having acetylcholine receptors that are sensitive to muscarine but not to nicotine.

muscarinic

pertaining to the transmission of nerve impulses mediated by muscarinic receptors; these may be adrenergic or cholinergic.

muscarinic activity
includes slowing and reduced stroke volume of the heart, bronchiolar constriction, arteriolar dilatation, increased tone, motility and secretion in the alimentary tract, and increases in salivation and lacrimation.
muscarinic blocking agents
block muscarinic receptors, e.g. atropine and the synthetic agents homatropine, methantheline, propantheline and methylatropine.
muscarinic receptors
cholinergic receptors of autonomic effector cells (and also on some autonomic ganglion cells and some central neurons) that are stimulated by muscarine and parasympathomimetic drugs and antagonized by atropine.
References in periodicals archive ?
The muscarinic system has shown enormous promise as a therapeutic target for the treatment of schizophrenia, but development efforts have been limited by tolerability concerns," said Alan Brier, M.
Beta 1 -adrenoceptors and muscarinic 2 receptors primarily affect heart rate, and beta 2-adrenoceptors and muscarinic 3 receptors primarily affect blood pressure.
It has been reported that anisodamine, a widely prescribed muscarinic receptor antagonist, could exert antiflammatory effects through upregulating [beta]-arrestin-1 (26).
These results indicate that the activation of SERCA and muscarinic receptors may play an important role in the effect of DECC on the cardiac contractility, heart rate and coronary flow.
Tolenix™ (THVD-201), a novel combination of muscarinic agonist (tolterodine) and muscarinic agonist (pilocarpine), is efficacious in OAB with less dry mouth compared to tolterodine alone [EAU abstract #402].
The receptors on the ganglion cells are generally thought to be nicotinic, whereas those on the effector organs seem to be muscarinic (Wood, 2002).
Blocking muscarinic receptors differentially modulates cognitive performance during the presentation of emotionally salient stimuli in unipolar and bipolar patient groups," Dr.
The new product, which is a muscarinic receptor antagonist, can exert beneficial effects with once-a-day dosage.
The scientists focused on muscarinic receptors, which regulate the speed of the heart, contraction of the pupil, and other bodily functions.
Indeed, similar changes may occur in peripheral cholinergic and catecholaminergic pathways, where CPF exposure in neonatal rats enhances [beta]-adrenergic effects at the expense of muscarinic cholinergic actions (Meyer et al.
1,6) Muscarinic receptors are acetylcholine-binding receptors that have historically been demonstrated to be activated by muscarine and blocked by atropine.
Darifenacin, a selective muscarinic M3 receptor antagonist approved last month for the treatment of overactive bladder, doesn't affect cognition in the elderly at clinically effective doses, Richard B.