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muscarinic |
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muscarinic /mus·ca·rin·ic/ (mus?kah-rin´ik) denoting the cholinergic effects of muscarine on postganglionic parasympathetic neural impulses. muscarinic pertaining to the transmission of nerve impulses mediated by muscarinic receptors; these may be adrenergic or cholinergic. muscarinic activity includes slowing and reduced stroke volume of the heart, bronchiolar constriction, arteriolar dilatation, increased tone, motility and secretion in the alimentary tract, and increases in salivation and lacrimation. muscarinic blocking agents block muscarinic receptors, e.g. atropine and the synthetic agents homatropine, methantheline, propantheline and methylatropine. muscarinic receptors cholinergic receptors of autonomic effector cells (and also on some autonomic ganglion cells and some central neurons) that are stimulated by muscarine and parasympathomimetic drugs and antagonized by atropine. |
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