murine leukemia

mu·rine leu·ke·mi·a

a leukemic disorder of mice caused by a number of different type C retroviruses.
References in periodicals archive ?
Most commonly, the RT used here is the Moloney murine leukemia virus RT (M-MLV RT); in addition to its pure RT activities, it has other enzymatic functions which the technique will make use of.
org/content/326/5952/585) a paper published in the journal Science linked the disease to a mouse retrovirus called xenotropic murine leukemia virus-related virus, or XMRV, after finding traces of it in 68 chronic fatigue syndrome patients out of a 101-patient sample.
Zhao M, Kiyoi H, Yamamoto Y, Ito M, Towatari M, Omura S, Kitamura T, Ueda R, Saito H, Naoe T: In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.
Human colon adenocarcinoma cell line (colo 205), human hepatoma cell line (Hep G2), human murine leukemia cell line (WEHI-3), mouse melanoma cell line (B16-F1), human melanoma cell line (A375 S2) and promyelomonocytic cells line (HL-60) were obtained from the Food Industry Research and Development Institute (Shinchu, Taiwan).
To the Editor: Xenotropic murine leukemia virus-related virus (XMRV) is a recently described human retrovirus that has been associated with prostate cancer and chronic fatigue syndrome (CFS) (1,2).
In addition, results from a series of preclinical studies showed that CMX157 exhibited highly potent in vitro activity against human immunodeficiency virus (HIV), including HIV strains resistant to current therapies, and potent in vitro activity against xenotropic murine leukemia virus-related virus (XMRV), a blood-borne retrovirus recently associated with chronic fatigue syndrome (CFS).
The nation's public health is at stake as scientists report that 7% of samples taken from the blood supply in The United States shows positive for a family of murine leukemia viruses.
XRMV (xenotropic murine leukemia virus) has been found in 23% of 200 cancerous prostates but only 6% of noncancerous prostates studied by researchers.
XMRV, short for xenotropic murine leukemia virus-related virus, also shows up in some men with prostate cancer, particularly those with aggressive malignancies, another research team reported in September in the Proceedings of the National Academy of Sciences.
A study published in the October issue of the journal Science reported that many patients with chronic fatigue syndrome were infected with a recently discovered virus, the xenotropic murine leukemia virus- related virus ( XMRV) which probably descended from a group of viruses that cause cancer in mice.
For 5'-RACE, reverse transcription was conducted to synthesize RACE-ready cDNA using SuperScript II (Moloney murine leukemia virus reverse transcriptase, Invitrogen) and the primer GSP1.
Irrefutable evidence does confirm that the nonhuman retroviruses avian leukosis virus (ALV), bovine leukemia virus (BLV), feline leukemia virus (FeLV), and murine leukemia virus (MuLV) induce lymphoproliferative disease in birds, cattle, cats, and mice, respectively; all are usually associated with T-cell leukemias.

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