murine leukemia

mu·rine leu·ke·mi·a

a leukemic disorder of mice caused by a number of different type C retroviruses.
References in periodicals archive ?
PIM kinases named for the genomic site, Proviral Integration site of Moloney Murine leukemia virus.
12) This might be partially explained by the ability of NRAS to activate both v-raf-1 murine leukemia viral oncogene homolog 1 (CRAF) and the PI3K signaling pathway.
BLV, bovine leukemia virus; LTR, long terminal repeat (promoter region); gag, group-specific antigen (capsid region); pol, polymerase (reverse transcription); env, envelope; tax, trans-activating region of the X gene; RSV, Rous sarcoma virus; MSV, murine sarcoma virus; MMTV, mouse mammary tumor virus; MPMV, Mason- Pfizer monkey virus; MuLV, murine leukemia virus; FeLV, feline leukemia virus; FLK, fetal lamb kidney; STLV, simian T-cell leukemia virus; HTLV, human T-cell leukemia virus; HPV, human papillomavirus; EBV, Epstein-Barr virus; HERV, human endogenous retrovirus.
Most commonly, the RT used here is the Moloney murine leukemia virus RT (M-MLV RT); in addition to its pure RT activities, it has other enzymatic functions which the technique will make use of.
org/content/326/5952/585) a paper published in the journal Science linked the disease to a mouse retrovirus called xenotropic murine leukemia virus-related virus, or XMRV, after finding traces of it in 68 chronic fatigue syndrome patients out of a 101-patient sample.
Zhao M, Kiyoi H, Yamamoto Y, Ito M, Towatari M, Omura S, Kitamura T, Ueda R, Saito H, Naoe T: In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor.
Human colon adenocarcinoma cell line (colo 205), human hepatoma cell line (Hep G2), human murine leukemia cell line (WEHI-3), mouse melanoma cell line (B16-F1), human melanoma cell line (A375 S2) and promyelomonocytic cells line (HL-60) were obtained from the Food Industry Research and Development Institute (Shinchu, Taiwan).
The nation's public health is at stake as scientists report that 7% of samples taken from the blood supply in The United States shows positive for a family of murine leukemia viruses.
XRMV (xenotropic murine leukemia virus) has been found in 23% of 200 cancerous prostates but only 6% of noncancerous prostates studied by researchers.

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