murine acquired immunodeficiency syndrome


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murine acquired immunodeficiency syndrome

An AIDS-like condition in mice caused by a defective retrovirus, which is characterised by T- and B-cell dysfunction, polyclonal B-cell proliferation, B-cell lymphoma, lymphadenopathy, splenomegaly, hypergammaglobulinaemia, and increased infections.
 
Management
Cyclophosphamide.
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