muramyl dipeptide


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muramyl dipeptide

a component of the cell wall of the mycobacteria that is active in Freund's complete adjuvant and in purified form also used as an adjuvant. In both instances, it enhances T cell mediated immune responses.
References in periodicals archive ?
NOD2, a member of the NOD family, is a cytoplasmic molecule recognizing muramyl dipeptide, a peptidoglycan contained in the wall structure of Gram-positive and Gram-negative bacteria, and controlling apoptosis and inflammatory processes [5].
Effects of two bacterial products, muramyl dipeptide and endotoxin, on bone resorption in organ culture.
A NOD2-NALP1 complex mediates caspase-1-dependent IL-lbeta secretion in response to Bacillus anthracis infection and muramyl dipeptide.
It seems that bacterial peptidoglycan and muramyl dipeptide are responsible for its induction (Crofford and Wilder 1993).
This volume presents recent research into developments of nanoparticulate delivery systems for an immune modulating agent, glucosaminyl muramyl dipeptide, the main component of the bacterial, wall, with a discussion of applications to treat endometriosis.
Important factors include endotoxin, bacterial cell wall components (peptidoglycan, muramyl dipeptide, and lipoteichoic acid), and bacterial products such as staphylococcal enterotoxin B, toxic shock syndrome toxin-1, pseudomonas exotoxin A, and M protein of haemolytic group A streptococci.
Chronic hypersensitivity pneumonitis produced in the rabbit by the adjuvant effect of inhaled muramyl dipeptide (MDP).
Junovan (Mifamurtide - Liposomal Muramyl Tripeptide Phosphatidyl Ethanolamine, MTP-PE) is a fully synthetic lipophilic derivative of the muramyl dipeptide.
Lipopolysaccharide (LPS)- and muramyl dipeptide (MDP)-induced anorexia during refeeding following acute fasting: Characterization of brain cytokine and neuropeptide systems mRNA.