multistage model

mul·ti·stage mod·el

a mathematical model, mainly for carcinogenesis, based on the theory that a specific carcinogen may affect one among a number of stages in the development of cancer.
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com)-- Mobile app developer and web designer, Keyideas recently announced their plans to shift to a multistage model to create responsive eCommerce websites.
Keyideas has laid out seven unique features that form the foundation of their multistage model.
Their multistage model includes the following: Search and Identification, Selection and Negotiation, Purchasing products and services electronically, Product and service delivery, After-sales service.
These detailed data allow the researchers to econometrically evaluate a multistage model of production and interaction activities at the firm, and to analyze the relationships among key technologies, work practices, and output.
Some generalizations of the two-mutation model of carcinogenesis of Moolgavkar, Venzon, and Knudson, and of the multistage model of Armitage and Doll.
For chemicals that do not react with DNA, it is not appropriate to use the linearated multistage model to extrapolate cancer risks from high toxic doses t lower nontoxic exposures.
In liver cancer research with experimental animals, DEN is used either as a complete carcinogen or as an initiator in multistage models (5).
Therefore, in multistage models of hepatocarcinogenesis that are initiated by a necrogenic dose of DEN, promoting agents might better be started at least 5 weeks after DEN treatment, not 2 weeks as originally designed (5), when sex difference is one concern of the study.
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