multipotent adult progenitor cell


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multipotent adult progenitor cell

stem cells isolated from marrow of postnatal people.
Synonym(s): adult stem cell
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These 21 articles help readers understand the ravages of CHF and the successes and failures of optimal medical therapies and give the basic science behind stem cell research, including the different stem cell types (including hematopoietic, mesenchymal, multipotent adult progenitor cells, umbilical cord blood stem cells, endogenous cardiac stem cells and embryonic stem cells) and the critical physiological pathways including chemokine and homing factor expression, stem cell differentiation toward a cardiac myocyte phenotype and mechanisms of arrhythmia including electrical coupling.
The researchers reported earlier this year that multipotent adult progenitor cells proliferate abundantly in the lab and can differentiate into cells similar to liver cells.
Researchers observed that administration of Multipotent Adult Progenitor Cells (MAPC) following spinal cord injury in rat models prevented the retraction of neurons, a process referred to as "axonal dieback," reduced inflammation in the region of injury, and also promoted the regrowth of neurons.
The versatility of these bone marrow cells, which Verfaillie and her team call multipotent adult progenitor cells, or MAPCs, could make them invaluable in several clinical and research settings.
ATHX) announced that an international team of researchers has published study results demonstrating that Multipotent Adult Progenitor Cells (MAPC) increase the long-term survival of organ transplants in instances when the cell donor is not related to the patient or the organ donor, and also appear to alleviate the need for long-term immune suppression.
ATHX) announced die publication of articles in two journals that describe the potential for multipotent adult progenitor cells (MAPCs), or MultiStem cells, to provide benefit in autoimmune disease and in peripheral vascular disease (PVD), respectively.