multinucleated


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multinucleated

characterized by having more than one nucleus per cell.

multinucleated giant cell
see giant cell.
References in periodicals archive ?
Histologic analysis for both tissue sites showed a nonnecrotizing histiocytic dermal lymphohistiocytic infiltrate with scattered multinucleated giant cells, some demonstrating elastophagocytosis (Figure 2).
In 1979 Rosen first described the presence of Multinucleated Stromal Giant Cells (MSGCs) in the breast, as an incidental finding in breast specimens from 14 patients with breast carcinoma and concluded that these cells represented a non-neoplastic and possibly reparative process (3).
18) This tumor is characterized by the presence of markedly atypical nuclei in multinucleated giant cells and mononuclear spindle cells, along with frequent abnormal mitotic activity.
Histologically, the stromal cells in giant cell tumors show no cytologic atypia or mitotic figures and resemble the nuclei of the multinucleated giant cells in the background.
10) Multinucleated giant cells, foamy cells, and spindle-shaped cells may be encountered and, depending on sampling issues, might be confused with RDD or the aforementioned xanthogranulomatous diseases.
Multinucleated giant cells and naked highly abnormal nuclei are also seen (Figure 1, D).
This study cohort included only cases in which the original diagnosis was confirmed upon review and multinucleated giant cells were relatively abundant.
In the intermediate or densely cellular form, lesions are typically made up of plump, tightly packed fibroblasts that often form small bundles; this form also features a small myxoid component and multinucleated giant cells.
Cytologic findings consisted of granuloma, macrophages loaded with Leishman-Donovan bodies (Figure 2, A), multinucleated giant cells (Figure 2, B), binucleated-histiocyte (Reed-Sternberg-like) cells loaded with Leishman-Donovan bodies, free Leishman-Donovan bodies, acute and chronic inflammatory cells, atypical organisms, histiocytes, plasma cells and mast cells (Figure 2, C), Leishman-Donovan bodies in the vicinity of respiratory epithelium in nasal smears, and atypical intracytoplasmic Leishman-Donovan bodies with ballooning changes.
Similar to classic BD, pagetoid BD always shows full-level involvement of the epidermis, scattered multinucleated tumor giant cells, keratohyalin granules, single-cell keratinization, and intercellular bridges visible between pagetoid cells, while EMPD lesion contains pagetoid cells well demarcated from nearby epidermal cells, flattened basal layer, stratum corneum involved, acinar structures, and no intercellular bridge.
These sinusoidal spaces were bordered by few multinucleated giant cells.
Histologic examination of the cerebrum and spinal cord revealed multiple adult filarial nematodes surrounded by granulomatous inflammation with several multinucleated giant cells.