This protist was spherically shaped (approximately 10 [micro]m in diameter) and resembled haplosporidian-like multinucleate
organisms, but also had characteristics of hypertrophied host connective tissue cells containing tightly packed microcells (Fig.
An air sac biopsy was obtained by endoscopy, and histologic results revealed necrotizing airsacculitis, with a mixedcell population of macrophages, multinucleate
cells, and occasional degenerate heterophils.
When a normal structure of the tissue is damaged, satellite cells are able to divide and fuse resulting in the establishment of new multinucleate
e) Although the author's comment that "the most striking feature in our case, however, was the presence of cells with a single huge nucleus, rather than multinucleate
cells," some of the giant cells pictured in their article suggest multinucleation.
The characteristic bilobed or multinucleate
giant cells of
After the third mitotic division, the cell begins to lay down incomplete septa, separating the hypha into numerous multinucleate
There was evidence of a typical inflammatory response consisting of multinucleate
macrophages at weeks 4 and 12, whereas immediately after the exposure, we observed numerous polymorphonuclear neutrophils.
In the secretory type, a layer of tapetal cells remains intact around the anther locule, whereas in the plasmodial type a multinucleate
tapetal plasmodium is formed in the anther locule by degeneration of tapetal cell walls and fusion of their protoplasts.
giant cells, common in pigs infected with PCV2, were seen.
Affected cells are often multinucleate
, and they can have either ground-glass, steel-gray nuclear inclusions with marginated chromatin or eosinophilic nuclear Cowdry A inclusions (Figure 1, B).
In our results, it was found clearly that intraperitioneal injection of Staphylococcus aureus into mice increased hyperplasia of splenic follicles, and also caused appearance of many multinucleate
giant cells (similar to the situation in Fig.
Several of the cavernous vascular spaces had undergone necrosis with local infiltration of small numbers of epithelioid macrophages, multinucleate
giant cells, and occasional lymphocytes.