The patent belongs to BiondVaxs portfolio family titled Multimeric
Multi-Epitope Influenza Vaccines and has now been granted in over 30 countries.
vWF is a large, multimeric
protein secreted from endothelial cells.
These 13 mitochondrial proteins encode subunits constituting the mitochondrial multimeric
complexes involved in the electron transport chain and oxidative phosphorylation (Staton et al.
The C-terminal LG3 domain is critical for the aggregation of AChRs and other molecules at the NMJ, whereas LG1 and LG2 domain of agrin are involved in interacting with a-dystroglycan, which is a multimeric
transmembrane protein complex and is thought to be associated with structural stability of muscle cell membrane.
Although the impurities--transferrin (TF), serum albumin (SA), free IgM light chain (LC), and monomeric IgMs--were detected in the same samples as the multimeric
IgMs, the fractions were cleaner for the IgM with a pI of 7.
Pentraxins are acute phase proteins in multimeric
With biopharma's evolving pipeline of novel protein therapeutics, such as bispecific antibodies, multimeric
proteins and Fc-fusion proteins, CHO cells are being pushed to their productivity limits in drug development and manufacturing.
4) After docking onto the cytosolic tail of the lysosomal receptor, the substrate protein unfolds and crosses the lysosomal membrane through a multimeric
pore complex and is degraded in the lysosomal lumen.
A new von Willebrand factor (vWF) defect in a patient with factor VIII (FVIII) deficiency but with normal levels and multimeric
patterns of both plasma and platelet vWF.
Fernandez-Lafuente R (2009) Stabilization of multimeric
enzymes: strategies to prevent subunit dissociation.
receptor composed of two copies of the TLR4-MD2-LPS complex resulting initiation of signal transduction by recruiting intracellular adaptor molecules such as Myeloid differentiation factor 88 (MyD88), TIR-related adaptor protein inducing interferon (TRIF), TRIF-related adaptor molecule (TRAM), TIR domain containing adaptor protein (TIRAP) or MyD88 adaptor like (MAL), and Sterile-alpha and Armadillo motif-containing protein (SARM).
Gap junctions are cell-cell communication channels that consist of multimeric
proteins called connexins.