multicentric


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multicentric

/mul·ti·cen·tric/ (mul″te-sen´trik) polycentric.

multicentric

Medspeak
adjective Referring to that which occurs in many sites in the body, as in a multicentric malignancy; in general, multifocal is preferred.

Trial
adjective Referring to that which occurs in multiple medical centres or hospitals, as in a multicentric study; in general, multicentre is preferred.

multicentric

the same pathological lesion occurring in many different sites at the same time, e.g. multicentric periarticular calcinosis.
References in periodicals archive ?
Haukaas and colleagues reported that multicentric tumours during the initial diagnosis shorten the recurrence-free survival period; even if the tumour is low-grade and low-staged, it carries an important risk factor for recurrence.
Naycheva's second presentation titled "Transcorneal Electrical Stimulation Treatment for Patients with Retinitis Pigmentosa -- Summary of Results from the TESOLA Study -- a Multicentric Observational Study" highlights the results of 105 patients who were treated with OkuStim for 30 minutes weekly over a period of six months.
A prospective, multicentric, randomized, double-blind interventional study was carried out at three eye centers in Northern India.
The nine new antineoplastic agents and their indications are belinostat (Beleodaq) for peripheral T-cell lymphoma; blinatumomab (Blincyto) for acute lymphoblastic leukemia; ceritinib (Zykadia) for non-small cell lung cancer; idelalisib (Zydelig) for some types of leukemia and lymphoma; nivolumab (Opdivo) for metastatic melanoma; olaparib (Lynparza) for ovarian cancer; pembrolizumab (Keytruda) for unresectable or metastatic melanoma; ramucirumab (Cyramza) for gastric or gastroesophageal adenocarcinoma and metastatic non-small cell lung cancer; and siltuximab (Sylvant) for multicentric Castleman disease.
Molecular investigations of multicentric lymphoma in starlings (Sturnus vulgaris) have suggested a retroviral etiology.
Such growth, we contend, was made possible by three factors: 1) continued relevance of the PRME Principles; 2) sustained institutional support from influential stakeholders; and 3) a move toward a multicentric governance structure.
A lymph node biopsy was done and the histological findings confirmed features that were in keeping with early human herpesvirus type 8 (HHV-8)-associated multicentric Castleman's disease.
Moreover, clinicians treating adult and pediatric patients with known solitary or multicentric forms of myofibroma should be aware of its potential for airway obstruction.
With multicentric atypical papillomas spanning a large area of the right breast, local excision or lumpectomy had the potential of leaving behind disease and would have certainly resulted in suboptimal cosmetic outcome.
Food and Drug Administration (FDA) has approved SYLVANT (siltuximab) for the treatment of patients with multicentric Castleman s disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative.
Lungs showed moderate acute diffuse lymphoplasmacytic and neutrophilic interstitial pneumonia; severe multicentric lymphoid depletion and multifocal necrotizing hepatitis were also observed.
Multicentric Castleman's disease (MCD) is a rare lymphoproliferative disorder.

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