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mucosal neuroma syndrome

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mucosal neuroma syndrome
[mo̅o̅ko′säl noo͡ro′mä]
multiple endocrine neoplasia, type III.

neoplasia [ne″o-pla´zhah]
the formation of a neoplasm.
cervical intraepithelial neoplasia (CIN) dysplasia of the cervical epithelium, often premalignant, characterized by various degrees of hyperplasia, abnormal keratinization, and the presence of condylomata.
multiple endocrine neoplasia (MEN) a group of rare hereditary disorders of autonomous hyperfunction of more than one endocrine gland. In Type I (MEN I), called also Wermer's syndrome, there are tumors of the pituitary, parathyroid gland, and pancreatic islet cells in association with a high incidence of peptic ulcer. Type II (MEN II), called also Sipple's syndrome, is characterized by medullary carcinoma of the thyroid, pheochromocytoma, often bilateral and multiple, and parathyroid hyperplasia. Type III (MEN III), called also mucosal neuroma syndrome, resembles Type II except that parathyroid hyperplasia is rare, the mean survival time is shorter, and there may be neuromas and neurofibromas. All forms are transmitted as autosomal dominant traits.


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