mucopolysaccharidosis VII

mucopolysaccharidosis VII

An AR lysosomal storage disease of mice and men caused by β-glucuronidase deficiency, with accumulation of glycosaminoglycans–GAGs in brain and other tissues, resulting in progressive mental deterioration and death Treatment Transplanted neural progenitor cells into the cerebral ventricles of mice corrects lysosomal storage of GAGs in neurons and glia. See Beta-glucuronidase.