MUC16

(redirected from mucin 16, cell surface associated)

MUC16

A gene on chromosome 19p13.2 which encodes a protein that provides a protective lubricating barrier against particles and infectious agents at mucosal surfaces. It is more commonly known as CA125, and is a highly characteristic marker of ovarian carcinomas.
References in periodicals archive ?
Briefly, epithelial cell adhesion molecule (EPCAM; also known as GA733-2)-positive and mucin 1, cell surface associated (MUC1)-positive cells were targeted, followed by RNA isolation and subsequent gene expression analysis by reversetranscription (RT) and multiplex PCR, detecting the tumor-associated transcripts EPCAM, MUC1, and mucin 16, cell surface associated (MUC16; also known as CA125) (AdnaTest OvarianCancerDetect; AdnaGen AG).
8] Human genes: ERCC1, excision repair cross-complementation group 1; EPCAM, epithelial cell adhesion molecule (also known as GA733-2); MUC1, mucin 1, cell surface associated; MUC16, mucin 16, cell surface associated (also known as CA125); ACTB, actin, beta; PPIC, peptidylprolyl isomerase C (cyclophilin C).