Identification can be achieved with culture or microscopic examination of biopsy-obtained tissue in conjunction with specia l stains such as methenamine silver or mucicarmine
A variable proportion of cells have intracytoplasmic lumina containing demonstrable sialomucins with the mucicarmine
and Alcian blue stains.
The capsule of Cryptococcus stains deep red with mucicarmine
and this feature may be used to support the diagnosis.
Periodic acid-Schiff-diastase and mucicarmine
stains highlight abundant intracellular mucin within the goblet cells.
and periodic acid-Schiff diastase stains can be helpful to exclude, in most cases, neoplasms of renal, prostatic, or thyroid origin.
A rim of faint mucicarmine
positivity is common in the vacuoles of mesotheliomas and should not be considered a feature diagnostic of adenocarcinoma.
The eosinophilic material is periodic acid-Schiff-positive with diastase digestion, mucicarmine
negative, and immunohistochemically positive for surfactant proteins A, B, and C.
The most consistent feature of SMILE is the spacing of nuclei by mucin, which can be highlighted with a mucicarmine
3) Mucin can be demonstrated histochemically with stains such as periodic acid-- Schiff, mucicarmine
, or high iron diamine and Alcian blue, and it is regarded as a hallmark of ductal differentiation in the pancreas (Figure 1, A).
Results of tests with stains for bacteria and fungi (periodic acid-Schiff-D, Gomori methenamine silver, mucicarmine
, Fite, acid-fast bacilli-Kinyoun, and Brown-Hopps) were negative.