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moxalactam

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moxalactam /mox·a·lac·tam/ (mok″sah-lak´tam) a semisynthetic antibiotic chemically related to the third-generation cephalosporins and having a broad spectrum of antibacterial activity; used as the disodium salt.
moxalactam [mok´sah-lak″tam]
a third generation cephalosporinantibiotic having a broad spectrum of activity, effective against β-lactamase–producing strains of Haemophilus influenzae and gram-negative enteric bacilli, including multiple drug-resistant strains.

moxalactam
a third-generation cephalosporin antibiotic having an oxa-β-lactam ring and a broad spectrum of activity, effective against β-lactamase-producing strains of Haemophilus influenzae and gram-negative enteric bacilli, including multiple drug-resistant strains.


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We tested the following antimicrobial agents: amoxicillin, amoxicillin/clavulanic acid (coamoxiclav), ticarcillin, ticarcillin/clavulanic acid, piperacillin, piperacillin/ tazobactam, cefalothin, cefoxitin, cefotaxime, ceftazidime, cefepime, imipenem, moxalactam, aztreonam, nalidixic acid, norfloxacin, ciprofloxacin, gentamicin, tobramycin, netilmicin, amikacin, nitroxolin, fosfomycin, and sulfamethoxazole/sulfamethoxazole/trimethoprim (cotrimoxazole).
Media Antibiotic TSA Glu Suc Lac Sorb Chloramphenicol 11(R) 10(R) 15(I) 0(R)# Ciprofloxacin 28(S) 28(S) 29(S) 25(S)# Gentamicin 15(S) 15(S) 16(S) 9(R)# Sulfa/Trimethoprim 13(I) 21(S) 0(R)# 0(R)# Moxalactam 28(S) 22(I)# 27(S) 22(I)# Media Antibiotic NA Glu Suc Lac Sorb Chloramphenicol 12(R) 10(R)# 11(R) 11(R) Ciprofloxacin 20(I)# 28(S) 28(S) 26(S) Gentamicin 10(R)# 11.
The patient had been on intravenous moxalactam at 2 g every 8 hours prophylactically, but this was stopped after 3 days because of the lack of growth on culture.
 
 
 
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