mouse unit


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Al·len-Doi·sy u·nit

(al'ĕn-dwah'sē),
the quantity of estrogen capable of producing in a spayed mouse a characteristic change in the vaginal epithelium, namely, disappearance of leukocytes and appearance of cornified cells, as determined by a vaginal smear; equal approximately to one half of an estrone unit.
Synonym(s): mouse unit

mouse unit

An obsolete, semi-quantitative bioassay unit corresponding to the amount of oestrogen required to produce characteristic microscopic changes in the vaginal epithelium of ovarectomise mice.

Allen,

Edgar, U.S. endocrinologist, 1892-1943.
Allen-Doisy test - a test for estrogenic activity.
Allen-Doisy unit - the quantity of estrogen capable of producing in a spayed mouse a characteristic change in the vaginal epithelium. Synonym(s): mouse unit
References in periodicals archive ?
11] Perhaps larger doses--in the range of 300 mouse units (MU) during a 30-day period--might lead to an antibody response.