morphogen


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mor·pho·gen

(mōr'fō-jen),
A soluble molecule secreted at a distance from the target cells that specifies the fates of cells. A morphogen may specify more than one cell type by forming a concentration gradient.

morphogen

/mor·pho·gen/ (mor´fah-jen) a substance in embryonic tissue that forms a concentration gradient and influences morphogenesis.

morphogen

(môr′fō-jĕn′)
n.
Any of various chemicals in embryonic tissue that influence the movement and organization of cells during morphogenesis by forming a concentration gradient.

morphogen

[môr′fəjen]
1 a soluble substance that controls the embryonic differentiation of a cell or tissue.
2 a substance secreted by one group of cells that causes a specific change in the growth and differentiation of a different group.

morphogen

(1) Any substance (e.g., retinoic acid) that triggers growth, proliferation and differentiation of cells and tissues in a concentration-dependent fashion. 
(2) Any molecule that orchestrates the development of an organism from the stage of a single cell to early embryogenesis.
References in periodicals archive ?
Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens.
But some biologists have raised questions about the theory, which contends that physical features are necessarily tied to absolute concentrations of proteins within the morphogen gradient.
It's controlled by molecules called morphogens, which form concentration gradients along the head-to-tail axis, or other axes, of developing embryos.
One way to prove that argosomes ferry morphogens across the embryo would be to stop the vesicles in their tracks.
Such as: What happens before the morphogen genes turn on?
They recognised that a pattern shift like this was similar to the response that had been reported two decades earlier in Drosophila fruit flies in experiments that provided the first direct evidence for the existence of morphogens.
The studies already have stirred two deeply divided camps of developmental biologists: those who believe that a single master chemical, or morphogen, calls the shots during development, and those who believe that a subtle interplay between the embryonic cells themselves determines whether they will become part of a finger or a thumb.
MorphoGen uses adult tissue to isolate and proliferate uncommitted, pluripotent stem cells for both the company's tissue engineering and organ regeneration businesses.
In the June 28 NATURE, the Boston researchers report evidence for another potential morphogen.
com, Moore Diversified Products, Morphogen Pharmeceuticals, MostChoice.