Early fetal heads, and major and minor salivary glands were collected retrospectively and glands were classified according to morphodifferentiation stage.
To evaluate immunohistochemical expression patterns, the major and minor salivary glands were classified according to the five morphodifferentiation stages (prebud, initial bud, pseudoglandular, canalicular, and terminal bud stages) described by Tucker.
brevispora was identified as a fast-growing fungal species and could be considered a desirable material in morphodifferentiation
study and demonstration.
Histomorphometric examination has revealed that the talon cusp has normal enamel and dentin with a substantially enlarged pulp tissue, which suggests that talon tooth, may be a developmental anomaly originating in the stage of morphodifferentiation (10).
It is thought to occur during morphodifferentiation stage as a result of outward folding of inner enamel epithelial cells (precursors of ameloblasts) and transient focal hyperplasia of mesenchymal dental papilla (precursors of odontoblasts) or a combination of genetic and environmental factors (multifactorial) (2).
In multirooted teeth, morphodifferentiation
continues but the stimulating factors are not known yet.
Many developing systems can be disturbed simultaneously by teratogenic influences which operate over a long period of morphodifferentiation
The differential diagnosis of benign odontogenic tumors is based on a comparison of the degrees of tissue morphodifferentiation
Tooth size and shape occurs at the morphodifferentiation
stage of the tooth development which takes place at approximately the 18th week of embrionic development for permanent teeth [Pinkham et al.
This lesion takes place because, dental components are laid down in a disorganized manner, due to failure of normal morphodifferentiation.
1) Thus, the degree of morphodifferentiation varies from lesion to lesion, enclosed in the calcified/mineralized matrix.
Conclusions: The fact that the talon cusp has normal enamel and dentine layers with a substantial enlarged pulp tissue suggests that talon tooth may be a developmental anomaly originating in the stage of morphodifferentiation